Resources
2018_cellrep_nehme_combiningngn2programmingwith.png
Publication
Combining NGN2 programming with developmental patterning generates human excitatory neurons with NMDAR-mediated synaptic transmission
Author: Nehme R, Zuccaro E, Ghosh SD, Li C, Sherwood JL, Pietilainen O, Barrett LE, Limone F, Worringer KA, Kommineni S, Zang Y, Cacchiarelli D, Meissner A, Adolfsson R, Haggarty S, Madison J, Muller M, Arlotta P, Fu Z, Feng G, Eggan K.
Product: Neural Module, Maestro Pro, Maestro Edge, CytoView MEA Plate,
2018 ISSCR poster Castell
Poster
Functional phenotypic screening of patient iPSC-derived motor neurons in vitro HTS disease modeling with micro electrode arrays coupled with multi-variate analysis methods
Author: Castell MS, Schultz L, Jügelt K, Hendrickson M, Schröder OHU, Bader BM.
Product: Maestro Pro, Neural Module, Maestro Edge,
2018 ISSCR poster aoyama hypertrophic cardiomyopathy
Poster
Evaluation of hypertrophic cardiomyopathy using human induced pluripotent stem cell-derived cardiomyocytes reveals abnormal excitation contraction coupling
Author: Aoyama N, Liu J, Lor S, Czysz K, Feaster TK, Hilcove S, Jones E.
Product: Maestro Pro, Cardiac Module, Maestro Edge,
2018 isscr poster clements
Poster
Multiwell microelectrode array technology for the evaluation of human iPSC-derived neuron and cardiomyocyte development and maturation
Author: Clements M, Hayes HB, Nicolini AM, Arrowood CA, Clements IP, Millard DC.
Product: Maestro Pro, Neural Module, Cardiac Module, CytoView MEA Plate, Maestro Edge,
2018 ISSCR poster clements characterization of human ipsc
Poster
Characterization of human iPSC-derived cardiomyocyte electrophysiology with the Local Extracellular Action Potential (LEAP) assay
Author: Clements M, Hayes HB, Nicolini AM, Arrowood CA, Clements IP, Millard DC.
Product: Maestro Pro, Cardiac Module, Lumos MEA Plate, Lumos, Maestro Edge,
2018 imin poster clements functional network
Poster
Quantification of functional network electrophysiology from stem cell derived neurons with multiwell microelectrode array technology
Author: Clements M, Hayes HB, Nicolini AM, Arrowood CA, Millard DC.
Product: Maestro Pro, Neural Module, Maestro Edge,
2018_procnatlacadsciusa_muffat_humaninducedpluripotentstem.png Image
Publication
Human induced pluripotent stem cell-derived glial cells and neural progenitors display divergent responses to Zika and dengue infections
Author: Muffat J, Li Y, Omer A, Durbin A, Bosch I, Bakiasi G, Richards E, Meyer A, Gehrke L, Jaenisch R.
Product: Neural Module, Maestro Pro, Maestro Edge,
2018_nuerotoxicology_tukker_humanipscderivedneuronal.png
Publication
Human iPSC-derived neuronal models for in vitro neurotoxicity assessment
Author: Tukker AM, Wijnolts FMJ, de Groot A, Westerink RHS.
Product: Neural Module, Maestro Pro, Maestro Edge,
2018_neuropharmacology_jewett_dysregulationandrestorationof.png
Publication
Dysregulation and restoration of homeostatic network plasticity in fragile X syndrome mice
Author: Jewett KA, Lee KY, Eagleman DE, Soriano S, Tsai NP.
Product: Neural Module, Maestro Pro, Maestro Edge,
Axion Bio App Note Maturity
Application Note
Fast functional maturity
Author: Axion BioSystems
Product: Maestro Pro, Cardiac Module, CytoView MEA Plate, Maestro Edge,
2018_brjpharmacol_yang_reversepharmacogenomicscarbamazepinenormalizes.png
Publication
Reverse pharmacogenomics: carbamazepine normalizes activation and attenuates thermal hyperexcitability of sensory neurons due to Nav1.7 mutation I234T
Author: Yang Y, Adi T, Effraim PR, Chen L, Dib-Hajj SD, Waxman SG.
Product: Maestro Pro, Neural Module, CytoView MEA Plate, Maestro Edge,
2018_scirep_derosa_convergentpathwaysinidiopathic.png
Publication
Convergent pathways in idiopathic autism revealed by time course transcriptomic analysis of patient-derived neurons
Author: DeRosa BA, El Hokayem J, Artimovich E, Garcia-Serje C, Phillips AW, Van Booven D, Nestor JE, Wang L, Cuccaro ML, Vance JM, Pericak-Vance MA, Cukier HN, Nestor MW, Dykxhoorn DM.
Product: Neural Module, Maestro Pro, Maestro Edge, CytoView MEA Plate,
2018_elife_chia_ahomozygouslossof.png
Publication
A homozygous loss-of-function CAMK2A mutation causes growth delay, frequent seizures and severe intellectual disability
Author: Chia PH, Zhong FL, Niwa S, Bonnard C, Utami KH, Zeng R, Lee H, Eskin A, Nelson SF, Xie WH, Al-Tawalbeh S, El-Khateeb M, Shboul M, Pouladi MA, Al-Raqad M, Reversade B.
Product: Neural Module, Maestro Pro, Maestro Edge,
2016_sps_millard_cipaphaseiiautomated.png
Poster
CiPA Phase II: Validation Study Results
Author: Blinova K.
Product: Maestro Pro, Maestro Edge, Cardiac Module,
2018_plosone_moyer_pharmacologicalcharacterizationofpotent.png
Publication
Pharmacological characterization of potent and selective NaV1.7 inhibitors engineered from Chilobrachys jingzhao tarantula venom peptide JzTx-V
Author: Moyer BD, Murray JK, Ligutti J, Andrews K, Favreau P, Jordan JB, Lee JH, Liu D, Long J, Sham K, Shi L, Stöcklin R, Wu B, Yin R, Yu V, Zou A, Biswas K, Miranda LP.
Product: Neural Module, Maestro Pro, Maestro Edge,
(2018) Witkin et al. Bioisosteres of Ethyl 8-Ethynyl-6-(Pyridin-2-yl)-4H- benzo[f]imidazo [1, 5-a][1,4]diazepine-3-carboxylate (HZ-166) as Novel Alpha 2,3 Selective Potentiators of GABAA Receptors: Improved Bioavailability Enhances Anticonvulsant Efficacy
Publication
Bioisosteres of ethyl 8-ethynyl-6-(pyridin-2-yl)-4H-benzo[f]imidazo [1,5-a][1,4]diazepine-3-carboxylate (HZ-166) as novel alpha 2,3 selective potentiators of GABAA receptors: improved bioavailability enhances anticonvulsant efficacy
Author: Witkin JM, Smith JL, Ping X, Gleason SD, Poe MM, Li G, Jin X, Hobbs J, Schkeryantz JM, McDermott JS, Alatorre AI, Siemian JN, Cramer JW, Airey DC, Methuku KR, Tiruveedhula VVNPB, Jones TM, Crawford J, Krambis MJ, Fisher JL, Cook JM, Cerne R.
Product: Neural Module, Maestro Pro, Maestro Edge,
(2018) Sarkar et al. Efficient Generation of CA3 Neurons from Human Pluripotent Stem Cells Enables Modeling of Hippocampal Connectivity In Vitro
Publication
Efficient generation of CA3 neurons from human pluripotent stem cells enables modeling of hippocampal connectivity in vitro
Author: Sarkar A, Mei A, Paquola ACM, Stern S, Bardy C, Klug JR, Kim S, Neshat N, Kim HJ, Ku M, Shokhirev MN, Adamowicz DH, Marchetto MC, Jappelli R, Erwin JA, Padmanabhan K, Shtrahman M, Jin X, Gage FH.
Product: Neural Module, Maestro Pro, Maestro Edge,
Axion Bio - Culture Protocol - CDI Cardiomyocytes2
Culture Protocol
CDI iCell Cardiomyocytes^2 Application Protocol
Author: Axion BioSystems
Product: Maestro Pro, Cardiac Module, CytoView MEA Plate, Maestro Edge,
2018_toxicolsci_millard_crosssitereliabilityof.png
Publication
Cross-site reliability of human induced pluripotent stem-cell derived cardiomyocyte based safety assays using microelectrode arrays: Results from a blinded CiPA Pilot Study
Author: Millard D, Dang Q, Shi H, Zhang X, Strock C, Kraushaar U, Zeng H, Levesque P, Lu HR, Guillon JM, Wu JC, Li Y, Luerman G, Anson B, Guo L, Clements M, Abassi YA, Ross J, Pierson J, Gintant G.
Product: Maestro Pro, Maestro Edge, Cardiac Module,
2018_jove_sanchez_assessmentoftheeffects.png
Publication
Assessment of the effects of endocrine disrupting compounds on the development of vertebrate neural network function using multi-electrode arrays
Author: Sanchez KR, Mersha MD, Dhillon HS, Temburni MK.
Product: Neural Module,