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[PREPRINT] Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome
Author: Unda BK, Chalil L, Yoon S, Kilpatrick S, Xing S, Murtaza N, Cheng A, Afonso A, McCready E, Ronen G, Howe J, Caye-Eude A, Verloes A, Doble BW, Faivre L, Vitobello A, Scherer SW, Lu Y, Penzes P, and Singh KK.
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Thyroid hormones regulate cardiac repolarization and QT-interval related gene expression in hiPSC cardiomyocytes
Author: Ulivieri A, Lavra L, Magi F, Morgante A, Calò L, Polisca P, Salehi LB, and Sciacchitano S.
Product: Maestro Pro, Cardiac Module, CytoView MEA Plate,
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Astrocytic 4R tau expression drives astrocyte reactivity and dysfunction
Author: Ezerskiy LA, Schoch KM, Sato C, Beltcheva M, Horie K, Rigo F, Martynowicz R, Karch CM, Bateman RJ, and Miller TM.
Product: Maestro Edge, Neural Module, CytoView MEA Plate,
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Edaravone activates the GDNF/RET neurotrophic signaling pathway and protects mRNA-induced motor neurons from iPS cells
Author: Li Q, Feng Y, Xue Y, Zhan X, Fu Y, Gui G, Zhou W, Richard JP, Taga A, Li P, Mao X, Maragakis NJ, Ying M.
Product: Maestro Edge, Neural Module, CytoView MEA Plate,
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Inhibition of intracellular proton-sensitive Ca2+-permeable TRPV3 channels protects against ischemic brain injury
Author: Chen X, Zhang J, and Wang K.
Product: Maestro Edge, Neural Module, CytoView MEA Plate,
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SLC13A5/NaCT overexpression causes disrupted white matter integrity and an autistic-like phenotype
Author: Rigby MJ, Orefice NS, Lawton AJ, Shapiro SL, Yi SY, Dieterich IA, Frelka A, Miles HN, Pearce RA, Yu JPJ, Li L, Denu JM, and Pugielli L.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
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IDH Mutated Gliomas Promote Epileptogenesis through D-2-Hydroxyglutarate Dependent mTOR Hyperactivation
Author: Mortazavi A, Fayed I, Bachani M, Dowdy T, Jahanipour J, Khan A, Owotade J, Walbridge S, Inati SK, Steiner J, Wu J, Gilbert M, Yang CZ, Larion M, Maric D, Ksendzovsky A, and Zaghloul KA.
Product: Maestro Edge, Neural Module, CytoView MEA Plate,
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Product Brochure
Maestro Pro System - Brochure
Author: Axion BioSystems
Product: Maestro Pro,
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Dysfunction of striatal MeCP2 is associated with cognitive decline in a mouse model of Alzheimer’s disease
Author: Lee S, Kim TK, Choi JE, Choi Y, You M, Ryu J, Chun YL, Ham S, Hyeon SJ, Ryu H, Kim H-S, and Im H-I.
Product: Maestro Edge, Neural Module, CytoView MEA Plate,
2022 Journal of Medical Chemistry
Publication
Discovery of Novel Sphingosine-1-Phosphate-1 Receptor Agonists for the Treatment of Multiple Sclerosis
Author: Park SJ, Yeon SK, Kim Y, Kim HJ, Kim S, Kim J, Choi JW, Kim B, Lee EH, Kim R, Seo SH, Lee J, Kim JW, Lee H-Y, Hwang H, Bahn Y-S, Cheong E, Park J-H, and Park KD.
Product: Maestro Pro, Cardiac Module, CytoView MEA Plate,
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Functional Characterization of Human Pluripotent Stem Cell-Derived Models of the Brain with Microelectrode Arrays
Author: Pelkonen A, Pistono C, Klecki P, Gómez-Budia M, Dougalis A, Kontinnen H, Stanová I, Fagerlund I, Leinonen V, Korhonen P, and Malm T.
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Impact of High-Dose Irradiation on Human iPSC-Derived Cardiomyocytes Using Multi-Electrode Arrays: Implications for the Antiarrhythmic Effects of Cardiac Radioablation
Author: Kim JS, Choi SW, Park Y-G, Jim SJ, Choi CH, Cha M-J, and Chang JH.
Product: Maestro Edge, Cardiac Module, BioCircuit MEA Plate,
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FTH promotes the proliferation and renders the HCC cells specifically resist to ferroptosis by maintaining iron homeostasis
Author: Hu W, Zhou C, Jing Q, Li Y, Yang J, Yang C, Wang L, Hu J, Li H, Wang H, Yuan C, Zhou Y, Ren X, Tong X, Du J, and Wang Y.
Product: Maestro Z, Impedance Module, CytoView-Z Plate,
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Using hiPSC-CMs to Examine Mechanisms of Catecholaminergic Polymorphic Ventricular Tachycardia
Author: Arslanova A, Shafaattalab S, Ye K, Asghari P, Lin L, Kim B, Roston TM, Hove-Madsen L, Van Petegem F, Sanatani S, Moore E, Lynn F, Søndergaard M, Luo Y, Chen SRW, and Tibbits GF.
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Junctional instability in neuroepithelium and network hyperexcitability in a focal cortical dysplasia human model
Author: Avansini SH, Puppo F, Adams JW, Vieira AS, Coan AC, Rogerio F, Torres FR, Araújo PAOR, Martin M, Montenegro MA, Yasuda CL, Tedeschi H, Ghizoni E, França AFEC, Alvim MKM, Athié MC, Rocha CS, Almeida VS, Dias EV, Delay L, Molina E, Yaksh TL, Cendes F, Lopes Cendes I, and Muotri AR.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
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HDAC6 Inhibition Corrects Electrophysiological and Axonal Transport Deficits in a Human Stem Cell-Based Model of Charcot-Marie-Tooth Disease (Type 2D)
Author: Smith AST, Kim JH, Chun C, Gharai A, Moon HW, Kim EY, Nam SH, Ha N, Song JY, Chung KW, Doo HM, Hesson J, Mathieu J, Bothwell M, Choi BO, and Kim DH.
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E3 ubiquitin ligase Nedd4-2 exerts neuroprotective effects during endoplasmic reticulum stress
Author: Lodes DE, Zhu J, and Tsai N-P.
Product: Neural Module,
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Integrated Omic Analyses Identify Pathways and Transcriptomic Regulators Associated with Chemical Alterations of in Vitro Neural Network Formation
Author: Marable CA, Frank CL, Seim RF, Hester S, Henderson WM, Chorley B, and Shafer TJ.
Product: Maestro Edge, Neural Module, CytoView MEA Plate,
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Human Spinal Organoid-on-a-Chip to Model Nociceptive Circuitry for Pain Therapeutics Discovery
Author: Ao Z, Cai H, Wu Z, Krzesniak J, Tian C, Lai YY, Mackie K, and Guo F.
Product: Maestro Edge, Neural Module, CytoView MEA Plate,
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Assessment of cerebral spinal fluid biomarkers and microRNA-mediated disease mechanisms in spinal muscular atrophy patient samples
Author: Welby E, Rehborg RJ, Harmelink M, and Ebert AD.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,