Neural Organoid Insights

Neural Organoid Brain Image

Neural organoids are three-dimensional, self-organizing cellular models generated from human pluripotent stem cells or primary tissues. Because these advanced 3D models can recapitulate many features of the human brain in vitro, neuroscientists are increasingly relying on neural organoids to investigate neurodevelopmental pathways, establish phenotypic models of disease, examine the impact of neurotoxicants, and explore unprecedented therapeutic strategies including precision and neuroregenerative medicine.

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Discover how Axion’s next-generation live-cell analysis tools can accelerate your disease research and drug discovery workflows:

>> Maestro multielectrode array (MEA) platform Assess key parameters of neural network function in real time with Axion’s nonstop, noninvasive, label-free Maestro MEA and powerful, intuitive software.

>> Omni imaging platform Visualize the growth, differentiation, cell morphology, and cell viability of neural organoids as they develop with Axion’s automated, AI-supported live-cell imaging tools.


See how organoids are transforming neuroscience research   >> 



Coffee Break Webinars

Sit back with a cup of coffee and enjoy these 10 minute webinars.

Mike Clements webinar on neural organoid workflow presented at WORD+
Standardizing organoid production and analysis
Author: Mike Clements
Product: Omni and Omni Pro 12, Confluency Module, SpheroGuide MEA Plate,
Spectrum in a Dish video
Coffee Break Webinar
The spectrum in a dish: Using neurophysiology to build a human iPSC model of autism
Author: Michael Nestor, PhD
Product: Maestro Pro, Neural Module, CytoView MEA Plate,



PBS Documentary: The Cannabis Question

Start watching at 22:50 to see how Dr. Alysson Muotri is using neural organoids to explore the impact of CBD on autism spectrum disorder.




Browse 35 selected publications illustrating how scientists around the world are using neural organoids for disease research and therapeutic discovery.

Disease research

16p11.2 disorders


Alzheimer’s disease

Autism spectrum disorders

Congenital central hypoventilation syndrome (CCHS)

Focal cortical dysplasia


Hypothalamus disorders

Myasthenia gravis (NMJ)

Noonan syndrome


PACS1 syndrome


Parkinson's Disease



Rett syndrome


Viral infection


Neurodevelopment and neurodegeneration




Regenerative medicine


Organoid development and optimization



Application Notes and Culture Protocols

Learn how easy it is to monitor neural organoids on Axion's hands-free, automated platforms.



In the News

Learn about opportunities and challenges in neural organoid technology.