Resources
Human Molecular Genetics, 10 December 2025
Publication
PTEN variant and genetic backgrounds combine to modify cerebellar neuronal differentiation in autism spectrum disorder
Author: Y. Chen, S. Fu, T. P H Sit, and A. Wynshaw-Boris
Product: Maestro MEA, Neural Module, CytoView MEA Plate,
Scientific Reports, 25 November 2025
Publication
High-throughput transcriptomic screening reveals entrectinib as a repositioning opportunity in 19q12 autism spectrum disorder
Author: D. Guin, U. Haditsch, J. J. Bellucci, S. Topka, K. E. Dyer, G. A. Rivera Del Toro, M. R. Blanco, N. F. Downs, N. Perfito, A. Mahadevan, and C. M. Moxham
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
Stem Cell Reports, 20 November 2025
Publication
Hypersynchronous iPSC-derived SHANK2 neuronal networks are rescued by mGluR5 agonism
Author: F. P. McCready, K. S. Pradeepan, M. Khaki, W. Wei, M. Guevara-Ferrer, N. Matusiak, B. Feng, A. Piekna, J. Martinez-Trujillo, and J. Ellis
Product: Maestro MEA, Neural Module, CytoView MEA Plate,
Maestro MEA: Optimized for Organoids
Video
Advancing Organoid Research Through MEA Innovation
Axion BioSystems
Product: Maestro Edge, Maestro Pro, Neural Module, MEA Creator Kit, Organoid MEA,
Scientific Reports, 29 April 2025
Publication
Seizure-like behavior and hyperactivity in napb knockout zebrafish as a model for autism and epilepsy
Author: K. C. Shin, W. Hasan, G. Ali, D. Abdelrahman, T. Abuarja, L. W. Stanton, S. I. Da’as and Y. Park
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
Nature Communications, 06 February 2025
Publication
Endothelial SHANK3 regulates tight junctions in the neonatal mouse blood-brain barrier through β-Catenin signaling
Author: Y. Kim, M. Kim, S. Kim, R. Lee, Y. Ujihara, E. M. Marquez-Wilkins, Y. Jiang, E. Yang, H. Kim, C. Lee, C. Park, and I. H. Kim
Product: Maestro Z, Impedance Module, CytoView-Z Plate,
Molecular Psychiatry, 30 September 2024
Publication
Dysregulation of miRNA expression and excitation in MEF2C autism patient hiPSC-neurons and cerebral organoids
Author: D. Trudler, S. Ghatak, M. Bula, J. Parker, M. Talantova, M. Luevanos, S. Labra, T. Grabauskas, S. M. Noveral, M. Teranaka, E. Schahrer, N. Dolatabadi, C. Bakker, K. Lopez, A. Sultan, P. Patel, A. Chan, Y. Choi, R. Kawaguchi, P. Stankiewicz, I. Garcia-Bassets, P. Kozbial, M. G. Rosenfeld, N. Nakanishi, D. H. Geschwind, S. F. Chan, W. Lin, N. J. Schork, R. Ambasudhan and S. A. Lipton
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
Brain, Behavior, and Immunity, 5 September 2024
Publication
Bi-allelic NRXN1α deletion in microglia derived from iPSC of an autistic patient increases interleukin-6 production and impairs supporting function on neuronal networking
Author: R. Bose, M. Posada-Pérez, E. Karvela, M. Skandik, L. Keane, A. Falk, S. Spulber, B. Joseph, and S. Ceccatelli
Product: Maestro Edge, CytoView MEA Plate, Neural Module,
Nature Communications, Aug 2024
Publication
Proximity analysis of native proteomes reveals phenotypic modifiers in a mouse model of autism and related neurodevelopmental conditions
Author: Y. Gao, D. Shonai, M. Trn, J. Zhao, E. J. Soderblom, S. A. Garcia-Moreno, C. A. Gersbach, W. C. Wetsel, G. Dawson, D. Velmeshev, Y. Jiang, L. G. Sloofman, J. D. Buxbaum and S. H. Soderling
Product: Maestro Pro, Neural Module, Cardiac Module,
International Journal of Molecular Sciences, 26 July 2024
Publication
Bioenergetic and Inflammatory Alterations in Regressed and Non-Regressed Patients with Autism Spectrum Disorder
Author: M. Gevezova, Z. Ivanov, I. Pacheva, E. Timova, M. Kazakova, E. Kovacheva, I. Ivanov, and V. Sarafian
Product: Exact FL, Cell Counting Module,
Cell Reports Publication, May 2024
Publication
Synergistic hyperactivation of both mTORC1 and mTORC2 underlies the neural abnormalities of PTEN-deficient human neurons and cortical organoids
Author: N. K. Dhaliwal, O. Y. Weng, X. Dong, A. Bhattacharya, M. Ahmed, H. Nishimura, W. W.Y. Choi, A. Aggarwal, B. W. Luikart, Q. Shu, X. Li, M. D. Wilson, J. Moffat, L. Y. Wang, J. Muffat, and Y. Li
Product: Maestro Edge, Neural Module, CytoView MEA Plate,
Role of mGluR7 in Fragile X syndrome_V. Kumar
Poster
Role of mGluR7 in Fragile X syndrome
Author: V. Kumar, K. Y. Lee, A. Acharya, M. S. Babik, and N. P. Tsai
Product: Maestro Edge, Neural Module, CytoView MEA Plate,
Neural Organoid Workflow Webinar
Video
Standardizing organoid production and analysis
Mike Clements, PhD
Product: Omni, Maestro Pro, iPSC Module, Clonogenic Assay Module, Organoid Analysis Module, Neural Module, MEA Viability Module, SpheroGuide MEA Plate, CytoView MEA Plate,
Cell Reports Publication, Feb 2024
Publication
Loss of GTF2I promotes neuronal apoptosis and synaptic reduction in human cellular models of neurodevelopment
Author: J. W. Adams, A. Vinokur, J. S. de Souza, C. Austria, B. S. Guerra, R. H. Herai, K. J. Wahlin, and A. R. Muotri
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
Autism Spectrum Disorder Publication Highlight Cover
Flyer
Autism Spectrum Disorder
Author:
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
Frontiers in Cellular Neuroscience, 15 January 2024
Publication
Disruption of the autism-associated gene SCN2A alters synaptic development and neuronal signaling in patient iPSC-glutamatergic neurons
Author: C. O. Brown, J. A. Uy, N. Murtaza, E. Rosa, A. Alfonso, B. M. Dave, S. Kilpatrick, A. A. Cheng, S. H. White, S. W. Scherer, K. K. Singh, and K. K. Singh
Product: Maestro Edge, Neural Module, CytoView MEA Plate,
Cell Press Publication, October 2023
Publication
Species-specific FMRP regulation of RACK1 is critical for prenatal cortical development
Author: M. Shen, C. L. Sirois, Y. Guo, M. Li, Q. Dong, N. M. Méndez-Albelo, Y. Gao, S. Khullar, L. Kissel, S. O. Sandoval, N. E. Wolkoff, S. X. Huang, Z. Xu, J. E. Bryan, A. M. Contractor, T. Korabelnikov, I. A. Glass, D. Doherty, Birth Defects Research Laboratory, J. E. Levine, A. M.M. Sousa, Q. Chang, A. Bhattacharyya, D. Wang, D. M. Werling, and X. Zhao
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
AJHG Publication, Oct 2023
Publication
Heterozygous deletion of the autism-associated gene CHD8 impairs synaptic function through widespread changes in gene expression and chromatin compaction
Author: X. Shi, C. Lu, A. Corman, A. Nikish, Y. Zhou, R. J. Platt, I. Iossifov, F. Zhang, J. Q. Pan, and N. E. Sanjana


Product: Maestro Edge, Neural Module, CytoView MEA Plate,
Molecular Neurobiology, 08 August 2023
Publication
Deletion of TRPC6, an Autism Risk Gene, Induces Hyperexcitability in Cortical Neurons Derived from Human Pluripotent Stem Cells
Author: K. C. Shin, G. Ali, H. Y. A. Moussa, V. Gupta, A. de la Fuente, H.-G. Kim, L. W. Stanton, and Y. Park
Product: Maestro Edge, Neural Module, CytoView MEA Plate,
Nature Communications Publication, 26 June 2023
Publication
Elevated levels of FMRP-target MAP1B impair human and mouse neuronal development and mouse social behaviors via autophagy pathway
Author: Y. Guo, M. Shen, Q. Dong, N. M. Méndez-Albelo, S. X. Huang, C. L. Sirois, J. Le, M. Li, E. D. Jarzembowski, K. A. Schoeller, M. E. Stockton, V. L. Horner, A. M. M. Sousa, Y. Gao, Birth Defects Research Laboratory, J. E. Levine, D. Wang, Q. Chang & X. Zhao
Product: Maestro Edge, Neural Module, CytoView MEA Plate,