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2020_journalofclinicalinvestigation_song_humanautologousipscderived
Publication
Human autologous iPSC-derived dopaminergic progenitors restore motor function in Parkinson's disease models
Author: Song B, Cha Y, Ko S, Jeon J, Lee N, Seo H, Park KJ, Lee IH, Lopes C, Feitosa M, Luna MJ, Jung JH, Kim J, Hwang D, Cohen BM, Teicher MH, Leblanc P, Carter BS, Kordower JH, Bolshakov VY, Kong SW, Schweitzer JS, Kim KS.
Product: Maestro Pro, Neural Module, CytoView MEA Plate, Maestro Edge,
2020_altex_tukker_towardsanimalfreeneurotoxicity.png
Publication
Towards Animal-Free Neurotoxicity Screening: Applicability of hiPSC-Derived Neuronal Models for In Vitro Seizure Liability Assessment
Author: Tukker AM, van Kleef, RGDM, Wijnolts FMJ, de Groot, A, and Westerink RHS.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
(2019) Zwartsen et al. Cardiotoxicity screening of illicit drugs and new psychoactive substances (NPS) in human iPSC-derived cardiomyocytes using microelectrode array (MEA) recordings
Publication
Cardiotoxicity screening of illicit drugs and new psychoactive substances (NPS) in human iPSC-derived cardiomyocytes using microelectrode array (MEA) recordings
Author: Zwartsen A, de Korte T, Nacken P, de Lange DW, Westerink RHS, Hondebrink L.
Product: Maestro Pro, Maestro Edge, Cardiac Module,
(2019) Grijalva et al. Engineered cardiac pacemaker nodes created by TBX18 gene transfer overcome source-sink mismatch
Publication
Engineered cardiac pacemaker nodes created by TBX18 gene transfer overcome source-sink mismatch
Author: Grijalva SI, Gu J, Li J, Fernandez N, Fan J, Sung JH, Lee SY, Herndon C, Buckley EM, Park SJ, Fenton FH, Cho HC.
Product: Maestro Pro, Maestro Edge, CytoView MEA Plate, Cardiac Module,
2019_actabiomater_atmaramani_rutheniumoxidebasedmicroelectrode.png
Publication
Ruthenium oxide based microelectrode arrays for in vitro and in vivo neural recording and stimulation
Author: Atmaramani R, Chakraborty B, Rihani RT, Usoro J, Hammack A, Abbott J, Nnoromele P, Black BJ, Pancrazio JJ, Cogan SF.
Product: Maestro Pro, Neural Module, Maestro Edge,
2019_stemcellres_leitner_immaturemdaneuronsameliorate.png
Publication
Immature mDA neurons ameliorate motor deficits in a 6-OHDA Parkinson's disease mouse model and are functional after cryopreservation
Author: Leitner D, Ramamoorthy M, Dejosez M, Zwaka TP.
Product: Maestro Pro, Neural Module, Maestro Edge,
2019_cardiovascres_perry_pharmacologicalactivationofikr.png
Publication
Pharmacological activation of IKr in models of long QT Type 2 risks overcorrection of repolarization
Author: Perry MD, Ng CA, Mangala MM, Ng TYM, Hines AD, Liang W, Xu MJO, Hill AP, Vandenberg JI.
Product: Maestro Pro, Cardiac Module, Maestro Edge,
(2019) Miklas et al. TFPa/HADHA is required for fatty acid beta-oxidation and cardiolipin re-modeling in human cardiomyocytes
Publication
TFPa/HADHA is required for fatty acid beta-oxidation and cardiolipin re-modeling in human cardiomyocytes
Author: Miklas JW, Clark E, Levy S1, Detraux D, Leonard A, Beussman K, Showalter MR, Smith AT, Hofsteen P, Yang X, Macadangdang J, Manninen T, Raftery D, Madan A, Suomalainen A, Kim DH, Murry CE, Fiehn O, Sniadecki NJ, Wang Y, Ruohola-Baker H.
Product: Maestro Pro, Maestro Edge, Cardiac Module,
2019_neuropsychopharmacology_shiers_reversalofperipheralnerve.png
Publication
Reversal of peripheral nerve injury-induced neuropathic pain and cognitive dysfunction via genetic and tomivosertib targeting of MNK
Author: Shiers S, Mwirigi J, Pradhan G, Kume M, Black B, Barragan-Iglesias P, Moy JK, Dussor G, Pancrazio JJ, Kroener S, Price TJ.
Product: Maestro Pro, Neural Module, Maestro Edge,
2019_plosgenet_liu_novelrolesoferstress.png
Publication
Novel roles of ER stress in repressing neural activity and seizures through Mdm2- and p53-dependent protein translation
Author: Liu DC, Eagleman DE, Tsai NP.
Product: Maestro Pro, Neural Module,
2019_neuron_sohn_pathogenictauimpairsaxon.png
Publication
Pathogenic Tau Impairs Axon Initial Segment Plasticity and Excitability Homeostasis
Author: Sohn PD, Huang CT, Yan R, Fan L, Tracy TE, Camargo CM, Montgomery KM, Arhar T, Mok SA, Freilich R, Baik J, He M, Gong S, Roberson ED, Karch CM, Gestwicki JE, Xu K, Kosik KS, Gan L.
Product: Neural Module, Maestro Pro, Maestro Edge,
2019_expmolmed_gu_inducedcardiacpacemakercells.png
Publication
Induced cardiac pacemaker cells survive metabolic stress owing to their low metabolic demand
Author: Gu JM, Grijalva SI, Fernandez N, Kim E, Foster DB, Cho HC.
Product: Maestro Pro, Maestro Edge, Cardiac Module,
(2019) Kumar et al. Assessment of temporal functional changes and miRNA profling of human iPSC-derived cardiomyocytes
Publication
Assessment of temporal functional changes and miRNA profiling of human iPSC-derived cardiomyocytes
Author: Kumar N, Dougherty JA, Manring HR, Elmadbouh I, Mergaye M, Czirok A, Greta Isai D, Belevych AE, Yu L, Janssen PML, Fadda P, Gyorke S, Ackermann MA, Angelos MG, Khan M.
Product: Maestro Edge, CytoView MEA Plate, Cardiac Module,
2019_cellstemcell_trujillo_complexoscillatorywavesemerging.png
Publication
Complex oscillatory waves emerging from cortical organoids model early human brain network development
Author: Trujillo CA, Gao R, Negraes PD, Gu J, Buchanan J, Preissl S, Wang A, Wu W, Haddad GG, Chaim IA, Domissy A, Vandenberghe M, Devor A, Yeo GW, Voytek B, Muotri AR.
Product: Neural Module, Maestro Pro, Maestro Edge, CytoView MEA Plate,
2019_molpsychiatry_wang_structuralinteractionbetweendisc1.png
Publication
Structural interaction between DISC1 and ATF4 underlying transcriptional and synaptic dysregulation in an iPSC model of mental disorders
Author: Wang X, Ye F, Wen Z, Guo Z, Yu C, Huang WK, Rojas Ringeling F, Su Y, Zheng W, Zhou G, Christian KM, Song H, Zhang M, Ming GL.
Product: Neural Module, Maestro Pro, Maestro Edge, CytoView MEA Plate,
(2019) Amatya et al. Dynamical electrical complexity is reduced during neuronal differentiation in autism spectrum disorder
Publication
Dynamical electrical complexity is reduced during neuronal differentiation in autism spectrum disorder
Author: Amatya DN, Linker SB, Mendes APD, Santos R, Erikson G, Shokhirev MN, Zhou Y, Sharpee T, Gage FH, Marchetto MC, Kim Y.
Product: Neural Module, Maestro Pro, Maestro Edge,
2019_scirep_hayes_novelmethodforaction.png
Publication
Novel method for action potential measurements from intact cardiac monolayers with multiwell microelectrode array technology
Author: Hayes HB, Nicolini AM, Arrowood CA, Chvatal SA, Wolfson DW, Cho HC, Sullivan DD, Chal J, Fermini B, Clements M, Ross JD, Millard DC.
Product: Maestro Pro, Cardiac Module,
2019_biomatersci_cheng_enhanceddruginternalizationand.png
Publication
Enhanced drug internalization and therapeutic efficacy of PEGylated nanoparticles by one-step formulation with anti-mPEG bispecific antibody in intrinsic drug-resistant breast cancer
Author: Cheng YA, Chen IJ, Su YC, Cheng KW, Lu YC, Lin WW, Hsieh YC, Kao CH, Chen FM, Roffler SR, Cheng TL.
Product: Cardiac Module,
(2019) Moakley et al. Pharmacological Profiling of Purified Human Stem Cell-Derived and Primary Mouse Motor Neurons
Publication
Pharmacological profiling of purified human stem cell-derived and primary mouse motor neurons
Author: Moakley D, Koh J, Pereira JD, DuBreuil DM, Devlin AC, Berezovski E, Zhu K, Wainger BJ.
Product: Neural Module, Maestro Pro, Maestro Edge,
(2019) Kreir et al. Role of Kv7.2/Kv7.3 and M1 Muscarinic Receptors in the Regulation of Neuronal Excitability in hiPSC-Derived Neurons
Publication
Role of Kv7.2/Kv7.3 and M1 muscarinic receptors in the regulation of neuronal excitability in hiPSC-derived neurons
Author: Kreir M, De Bondt A, Van den Wyngaert I, Teuns G, Lu HR, Gallacher DJ.
Product: Neural Module, Maestro Pro, Maestro Edge,