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Pathophysiological metabolic changes associated with disease modify the proarrhythmic risk profile of drugs with potential to prolong repolarisation
Author: TeBay C, McArthur JR, Mangala M, Kerr N, Heitmann S, Perry MD, Windley MJ, Vandenberg JI, and Hill AP.
Product: Maestro Pro, Cardiac Module, CytoView MEA Plate,
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Publication
Marine and Anthropogenic Bromopyrroles Alter Cellular Ca 2+ Dynamics of Murine Cortical Neuronal Networks by Targeting the Ryanodine Receptor and Sarco/Endoplasmic Reticulum Ca 2+-ATPase
Author: Zheng J, Antrobus S, Feng W, Purdy TN, Moore BS, and Pessah IN.
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MEA viability application note
Application Note
Validation of a structure-function assay for neurotoxicity in primary and hiPSC-derived neurons
Author: Axion BioSystems
Product: MEA Viability Module, Maestro Pro,
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Publication
Mutations of the histone linker H1–4 in neurodevelopmental disorders and functional characterization of neurons expressing C-terminus frameshift mutant H1.4
Author: Tremblay MW, Green MV, Goldstein BM, Aldridge AI, Rosenfeld JA, Streff H, Tan WD, Craigen W, Bekheirnia N, Al Tala S, West AE, and Jiang YH.
Product: Maestro Edge, Neural Module, CytoView MEA Plate,
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Publication
Real-Time Monitoring of Levetiracetam Effect on the Electrophysiology of an Heterogenous Human iPSC-Derived Neuronal Cell Culture Using Microelectrode Array Technology
Author: Di Credico A, Gaggi G, Izzicupo P, Ferri L, Bonanni L, Iannetti G, Di Baldassarre A, and Ghinassi B.
Product: Maestro Edge, Neural Module, CytoView MEA Plate,
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Publication
Lipidomics Reveals Dysregulated Glycerophospholipid Metabolism in the Corpus Striatum of Mice Treated with Cefepime
Author: Liu X, Wei Q, Yang X, Wang X, Zhang J, Xu R, Zhang H, Wang S, Wan X, Jiang L, He Y, Li S, Chen R, Wang Y, Chen Y, Qin F, Chen Y, Dai Y, Li H, Zhao Y, Zhang H, Bu Q, Wang H, Tian J, Zhao Y, and Cen X.
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Gene‑corrected p.A30P SNCA patient‑derived isogenic neurons rescue neuronal branching and function
Author: Barbuti PA, Ohnmacht J, Santos BFR, Antony PM, Massart F, Cruciani G, Dording CM, Pavelka L, Casadei N, Kwon YJ, and Krüger R.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
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Poster
Establishing a human iPSC-derived neuron model of SLC35A2- associated epilepsy
Author: Lai D, Williams D, Sosicka P, Ressler AK, Freeze HH, Boland MJ, and EL Heinzen.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
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Poster
An in vitro model to study the association of genetic diversity and neurological conditions reveals novel genes in DYRK1A-related disorders and axonal injury linked to susceptibilty and resilience
Author: Cortes, D.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
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Poster
Mechanisms of maladaptive compensation in KCNQ2-related epilepsy in patient-specific iPSC derived neurons
Author: Simkin D, Wafa A, Gharib M, Marshall K, George AL, and Kiskinis E.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
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Poster
Microglial regulation of hyperexcitability in cortical neurons derived from human iPSCs carrying epilepsy-associated sodium channel Nav1.2 variant
Author: Que Z, Olivero-Acosta M, Zhang J, Wettchurack KW, Skarnes W, and Yang Y.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
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Poster
Multiplexed cell based assay of neuronal structure function for neurotoxicity and disease modeling
Author: Millard D, Sullivan D, and Hayes H.
Product: Maestro Pro, MEA Viability Module, CytoView MEA Plate,
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Publication
The Role of METTL3-Mediated N6-Methyladenosine (m6A) of JPH2 mRNA in Cyclophosphamide-Induced Cardiotoxicity
Author: Zhu M, Liu Y, Song Y, Zhang S, Hang C, Wu F, Lin X, Huang Z, Lan F, and Xu M.
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Poster
Evaluating neuronal, synaptic, and network function in stem cell models of neural development and disease
Author: Hayes H, Sullivan D, Millard D, and Clements M.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
Journal of the American Heart Association Publication, Nov 2021
Publication
Comparative Analysis of Blood‐Derived Endothelial Cells for Designing Next‐Generation Personalized Organ‐on‐Chips
Author: T. Mathur, J. J. Tronolone and A. Jain
Product: Lux,
Lipodomics Reveals dysregulated glycerophospholipid metabolism
Publication
Lipidomics Reveals Dysregulated Glycerophospholipid Metabolism in the Corpus Striatum of Mice Treated with Cefepime
Author: Liu X, Wei Q, Yang X, Wang X, Zhang J, Xu R, Zhang H, Wang S, Wan X, Jiang L, He Y, Li S, Chen R, Wang Y, Chen Y, Qin F, Chen Y, Dai Y, Li H, Zhao Y, Zhang H, Bu Q, Wang H, Tian J, Zhao Y, and Cen X.
Product: Maestro Edge, Neural Module, CytoView MEA Plate,
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Publication
Depletion of m6A reader protein YTHDC1 induces dilated cardiomyopathy by abnormal splicing of Titin
Author: Gao S, Sun H, Chen K, Gu X, Chen H, Jiang L, Chen L, Zhang S, Liu Y, Shi D, Liang D, Xu L, Yang J, Ruan Y, Chen H, Shen B, Ma H, and Chen YH.
Product: Maestro Pro, Cardiac Module, CytoView MEA Plate,
Yang paper on epilespy in J Neuroscience
Publication
Hyperexcitability and pharmacological responsiveness of cortical neurons derived from human iPSCs carrying epilepsy associated sodium channel Nav1.2-L1342P genetic variant
Author: Que Z, Olivero-Acosta MI, Zhang J, Eaton M, Tukker AM, Chen X, Wu J, Xie J, Xiao T, Wettschurack K, Yunis L, Shafer JM, Schaber JA, Rochet J-C, Bowman AB, Yuan C, Huang Z, Hu C-D, Trader DJ, Skarnes WC, Yang Y.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
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Effects of low temperature on electrophysiology and mechanophysiology of human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs)
Author: Kanade PP, Oyunbaatar N-E, Lee D-W.
Product: Maestro Pro, Cardiac Module, CytoView MEA Plate,
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Publication
Proarrhythmic effects induced by benzethonium chloride and domiphen bromide in vitro and in vivo
Author: Long Y, Hou J, Tang F, Lin Z, Huang X, Li W, Chen Y, Li Z, and Wu Z.
Product: Maestro Pro, Cardiac Module, BioCircuit MEA Plate,