Resources
Altered network and rescue of human neurons derived from individuals with early-onset genetic epilepsy
Publication
Altered network and rescue of human neurons derived from individuals with early-onset genetic epilepsy
Author: Negraes PD, Trujillo CA, Yu N-K, Wu W, Yao H, Liang N, Lautz JD, Kwok E, McClatchy D, Diedrich J, de Bartolome SM, Truong J, Szeto R, Tran T, Herai RH, Smith SEP, Haddad GG, Yates JR and Muotri AR.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
What is in vitro potency assay for cancer immunotherapy
Video
In vitro potency assays for cancer immunotherapy
Axion BioSystems
Product: Maestro ZHT, CytoView-Z Plate, GxP Impedance Module, Maestro Z, Impedance Module, Impedance Automation Module,
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News
Axion BioSystems Announces Formation of Scientific Advisory Board
Author: Axion BioSystems
Product: Maestro Pro, Maestro Edge, Maestro Z, Maestro ZHT,
2021 publication altered neuronal support with bipolar disorder
Publication
Altered neuronal support and inflammatory response in bipolar disorder patient-derived astrocytes
Author: Vadodaria KC, Mendes APD, Mei A, Racha V, Erikson G, Shokhirev MN, Oefner R, Heard KJ, McCarthy MJ, Eyler L, Kelsoe JR, Santos R, Marchetto MC, and Gage FH.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
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Publication
Method for selective ablation of undifferentiated human pluripotent stem cell populations for cell-based therapies
Author: Chour T, Tian L, Lau E, Thomas D, Itzhaki I, Malak O, Zhang JZ, Qin X, Wardak M, Liu Y, Chandy M, Black KE, Lam MP, Neofytou E, and Wu JC.
Product: Maestro Pro, Cardiac Module, BioCircuit MEA Plate,
2021 Publication cardiac laminopathy on MEA system
Publication
Chromatin compartment dynamics in a haploinsufficient model of cardiac laminopathy
Author: Bertero A, Fields PA, Smith AST, Leonard A, Beussman K, Sniadecki NJ, Kim D, Tse H, Pabon L, Shendure J, Noble WS, Murry CE
Product: Maestro Pro, Cardiac Module, CytoView MEA Plate,
Neanderthal mini-brain video
Coffee Break Webinar
Neanderthal mini-brains
Author: Cleber Trujillo, PhD
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
AARC conference poster on T-cell mediated targeting of glioblastoma
Poster
Kinetics and potency of GD2 CAR-T cell-mediated cytolysis of glioblastoma
Author: Axion BioSystems
Product: Maestro Z, Impedance Module, CytoView-Z Plate, Impedance Automation Module,
Application Note - Z prime - high throughput assays
Application Note
Validation of an Impedance-based Cytotoxicity Assay for High Throughput Screening
Author: Axion BioSystems
Product: Maestro ZHT, CytoView-Z Plate, Impedance Module, Maestro Z, GxP Impedance Module, Impedance Automation Module,
Cell Metabolism publication 2021 Aging skeletal muscle and brain and retina
Publication
Proteasome stress in skeletal muscle mounts a long-range protective response that delays retinal and brain aging
Author: Rai M, Coleman Z, Curley M, Nityanandam A, Platt A, Robles-Murguia M, Jiao, J, Finkelstein D, Wang Y-D, Xu B, Fan Y, Demontis F.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
Chemotheraphy neuropathy evaluated on hipsc-peripheral neurons in MEA assay
Publication
Investigation into the Role of ERK in Tyrosine Kinase Inhibitor-Induced Neuropathy
Author: Belair DG, Sudak K, Connelly K, Collins ND, Kopytek SJ, Kolaja KL.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
2021 Publication 3D engineered brain organoids and custom connection to Maestro MEA system
Publication
Three-dimensional, multifunctional neural interfaces for cortical spheroids and engineered assembloids
Author: Park Y, Franz CK, Ryu H, Luan H, Cotton KY, Kim JU, Chung TS, Zhao S, Vazquez-Guardado A, Yang DS, Li K, Avila R, Phillips JK, Quezada MJ, Jang H, Kwak SS, Won SM, Kwon K, Jeong H, Bandodkar AJ, Han M, Zhao H, Osher GR, Wang H, Lee KH, Zhang Y, Huang Y, Finan JD, Rogers JA.
Product: Maestro Pro, Neural Module,
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Publication
Autism-linked Cullin3 germline haploinsufficiency impacts cytoskeletal dynamics and cortical neurogenesis through RhoA signaling
Author: Amar M, Pramod AB, Yu NK, Herrera VM, Qiu LR, Moran-Losada P, Zhang P, Trujillo CA, Ellegood J, Urresti J, Chau K, Diedrich J, Chen J, Gutierrez J, Sebat J, Ramanathan D, Lerch JP, Yates JR 3rd, Muotri AR, and Iakoucheva LM.
Product:
What is MEA (microelectrode array) video
Video
What is MEA (microelectrode array) technology?
Axion BioSystems
Product: Maestro Pro, Maestro Edge, Neural Module, Cardiac Module, BioCircuit MEA Plate, CytoView MEA Plate,
human stem-cell derived test system for neuronal signaling on multiwell MEA system
Publication
A human stem cell‑derived test system for agents modifying neuronal N‑methyl‑d‑aspartate‑type glutamate receptor Ca2+‑signalling
Author: Klima S, Brüll M, Spreng A-S, Suciu I, Falt T, Schwamborn JC, Waldmann T, Karreman C, Leist M.
Product: Maestro Edge, Neural Module, CytoView MEA Plate,
isogenic sets
Publication
Isogenic sets of hiPSC-CMs harboring distinct KCNH2 mutations differ functionally and in susceptibility to drug-induced arrhythmias
Author: Brandao K, van den Brink L, Miller DC, Grandela C, van Meer BJ, Mol MPH, de Korte T, Tertoolen LGJ, Mummery CL, Sala L, Verkerk AO, and P. Davis R
Product: Maestro Pro, Cardiac Module, Maestro Edge,
sfN 2021 Poster on brain turmors and epilepsy mechanism recorded on multiwell MEA system
Poster
IDH mutated tumors promote epileptogenesis via D-2-HG dependent mTOR hyperactivation
Author: Mortazavi A, Fayed I, Bachani M, Ksendzovsky A, Maric D, Dowdy T, Larion M, Yang CZ, Zaghloul KA.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
Acute Brain Slice Protocol on MEA platform
Culture Protocol
Acute Brain Slice Protocol
Author: Axion BioSystems
Product: Maestro Pro, Neural Module, CytoView MEA Plate, Maestro Edge,
2021 Rybak wolf brain organoids with herpes
Publication
Neurodegeneration in human brain organoids infected with herpes simplex virus type 1
Author: Rybak-Wolf A, Wyler E, Legnini I, Loewa A, Glažar P, Kim SJ, Pentimalli TM, Martinez AO, Beyersdorf B, Woehler A, Landthaler M and Rajewsky N.
Product: Maestro Pro, Neural Module, BioCircuit MEA Plate,
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Publication
The enhancement of activity rescues the establishment of Mecp2 null neuronal phenotypes
Author: Scaramuzza L, De Rocco G, Desiato G, Cobolli Gigli C, Chiacchiaretta M, Mirabella F, Pozzi D, De Simone M, Conforti P, Pagani M, Benfenati F, Cesca F, Bedogni F, and Landsberger N.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,