Resources
Journal of Medicinal Chemistry, 23 January 2026
Publication
Development of Novel Small-Molecule Targeting SCN1A-Associated Severe Myoclonic Epilepsy of Infancy
Author: D. G. Kim, K. S. Hwang, S. H. Ahn, S. S. Kim, Y. Son, S. B. Park, W. H. Jung, D. S. Shin, S. H. Cho, B. W. Choi, P. Kim, Y. Heo, M. Kim, J. Y. Yang, K. R. Lee, H. A. Lee, J. Kim, H. C. Kang, K. Y. Kim, M. A. Bae, and J. H. Ahn
Product: Maestro Edge, Neural Module, CytoView MEA Plate,
Brain, 15 November 2025
Publication
SUR1-TRPM4 is expressed in human epilepsy and promotes neuron hyperactivity and seizures in rodents
Author: M. B. Moyer, S. Ivanova, K. Keledijan, M. Kreinbrink, J. Langbein, P. Yang, D. McAfee, U. Boddeti, Z. Khan, J. Owotade, T. Zhang, D. R. Benavides, J. Diamond, K. Zaghloul, M. Bachani, V. Gerzanich, J. M. Simard, and A. Ksendzovsky
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
Cerebral organoids to model seizures and for the discovery of antiseizure medicine
Coffee Break Webinar
Cerebral organoids to model seizures and for the discovery of antiseizure medicine
Author: R. Halliwell
Product: Maestro Edge, Neural Module, CytoView MEA Plate,
Neurobiology of Disease, 25 September 2025
Publication
Human iPSC-derived glutamatergic neurons with pathogenic KCNQ2 variants display hyperactive bursting phenotypes
Author: M. Sundberg, C. Shum, E. M. Norabuena, N. R. Makhortova, C. Chen, L. Yu, E. V. Wightman, K. Kim, S. Y. Han, J. Howe, A. Poduri, E. D. Buttermore, S. W. Scherer, and M. Sahin
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
Neuroscience Research, 19 September 2025
Publication
Abnormalities in the functional activity of neural networks in a human iPSC model of Dravet syndrome
Author: R. Mzezewa, T. Hyvärinen, O. Kulta, A. Vinogradov, E. Pesu, L. Isosaari, V. Vuolanto, F. E. Kapucu, J. Schuster, N. Dahl, and S. Narkilahti
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
Translational Psychiatry, 29 August 2025
Publication
Altered development and network connectivity in a human neuronal model of 15q11.2 deletion-related neurodevelopmental disorders
Author: C. W. Habela, S. Liu, A. Taga, S. Oddoye, R. Dastgheyb, N. Haughey, D. E. Bergles, H. Song, G. Ming, and N. J. Maragakis
Product: Maestro Edge, Neural Module, CytoView MEA Plate,
Maestro MEA: Optimized for Organoids
Video
Advancing Organoid Research Through MEA Innovation
Axion BioSystems
Product: Maestro Edge, Maestro Pro, Neural Module, MEA Creator Kit, Organoid MEA,
Receptors, 20 June 2025
Publication
Human Stem Cell-Derived Neural Organoids for the Discovery of Antiseizure Agents
Author: H. Salmanzadeh and R. F. Halliwell
Product: Maestro Edge, Neural Module, CytoView MEA Plate,
Epilepsy Research, 17 May 2025
Publication
Functional evaluation of a rat model of KCNT1-related epilepsy
Author: N. Liu, Z. Lin, H. Song, A. Cai, X. Li, J. Zhang, D. Chang, T. Ji, Y. Wu, Z. Huang, Y. Jiang, and K. Gao
Product: Maestro MEA, Neural Module, CytoView MEA Plate,
Scientific Reports, 29 April 2025
Publication
Seizure-like behavior and hyperactivity in napb knockout zebrafish as a model for autism and epilepsy
Author: K. C. Shin, W. Hasan, G. Ali, D. Abdelrahman, T. Abuarja, L. W. Stanton, S. I. Da’as and Y. Park
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
Redox Biology, 13 February 2025
Publication
Selenium deficiency impedes maturation of parvalbumin interneurons, perineuronal nets, and neural network activity
Author: A. R. Sasuclark, M. Watanabe, K. Roshto, V. W. Kilonzo, Y. Zhang, and M. W. Pitts
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
Advanced Science, 31 December 2024
Publication
Personalized Human Astrocyte-Derived Region-Specific Forebrain Organoids Recapitulate Endogenous Pathological Features of Focal Cortical Dysplasia
Author: J. Xu, Y. Kong, N. Wang, H. Li, Y. Li, Z. Liu, Y. Yang, X. Yu, H. Liu, J. Ding, Y. Wang, R. Zhao, and Z. Shao
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
eNeuro, 18 December 2024
Publication
The Epilepsy–Aphasia Syndrome Gene, Cnksr2, Plays a Critical Role in the Anterior Cingulate Cortex Mediating Vocal Communication
Author: K. Hossain, E. Erata, L. Schiapparelli and S. H. Soderling
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
Brain, 26 October 2024
Publication
CACNA1A haploinsufficiency leads to reduced synaptic function and increased intrinsic excitability
Author: M. P. Hommersom, N. Doorn, S. Puvogel, E. I. Lewerissa, A. Mordelt, U. Ciptasari, F. Kampshoff, L. Dillen, E. van Beusekom, A. Oudakker, N. Kogo, A. M. Dolga, M. Frega, D. Schubert, B. P. C. van de Warrenburg, N. N. Kasri, and H. van Bokhoven
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
Frontiers in Network Physiology, 02 September 2024
Publication
Modeling seizure networks in neuron-glia cultures using microelectrode arrays
Author: U. Boddeti, J. Langbein, D. McAfee, M. Altshuler, M. Bachani, H. P. Zaveri, D. Spencer, K. A. Zaghloul, and A. Ksendzovsky
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
Nature Communications, 04 July 2024
Publication
A pH-sensitive closed-loop nanomachine to control hyperexcitability at the single neuron level
Author: Assunta Merolla, Caterina Michetti, Matteo Moschetta, Francesca Vacca, Lorenzo Ciano, Laura Emionite, Simonetta Astigiano, Alessandra Romei, Simone Horenkamp, Ken Berglund, Robert E. Gross, Fabrizia Cesca, Elisabetta Colombo and Fabio Benfenati
Product: Maestro Edge, Neural Module, CytoView MEA Plate,
Cell Reports Publication, May 2024
Publication
Synergistic hyperactivation of both mTORC1 and mTORC2 underlies the neural abnormalities of PTEN-deficient human neurons and cortical organoids
Author: N. K. Dhaliwal, O. Y. Weng, X. Dong, A. Bhattacharya, M. Ahmed, H. Nishimura, W. W.Y. Choi, A. Aggarwal, B. W. Luikart, Q. Shu, X. Li, M. D. Wilson, J. Moffat, L. Y. Wang, J. Muffat, and Y. Li
Product: Maestro Edge, Neural Module, CytoView MEA Plate,
Frontiers in Pharmacology Publication, May 2024
Publication
Antiseizure properties of fenamate NSAIDs determined in mature human stem-cell derived neuroglial circuits
Author: H. Salmanzadeh, and R. F. Halliwell
Product: Maestro Edge, Neural Module, CytoView MEA Plate,
Maestro Volt MEA system launched by Axion BioSystems
News
Axion BioSystems Adds Affordable Maestro Volt to its Industry-Leading MEA System Lineup
Author: Axion BioSystems
Product: Maestro Volt, Neural Module, Cardiac Module, CytoView MEA Plate,
Neural Organoid Workflow Webinar
Video
Standardizing organoid production and analysis
Mike Clements, PhD
Product: Omni, Maestro Pro, iPSC Module, Clonogenic Assay Module, Organoid Analysis Module, Neural Module, MEA Viability Module, SpheroGuide MEA Plate, CytoView MEA Plate,