Resources
Molecular Psychiatry, 31 January 2026
Publication
SHANK3 deficiency alters early progenitor dynamics and reveals shared pathways with neurodegeneration
Author: E. Varella-Branco, E. Shephard, V. H. C. Toledo, I. C. Ramos, E. C. M. Lacerda, L. L. M. Carvalho, M. A. Fiuza, M. Paschalidis, C. I. S. Costa, A. C. S. Girardi, A. C. V. Krepischi, E. B. Casella, G. Polanczyk, K. Griesi-Oliveira, F. Papes, L. Alvizi, G. S. Kobayashi, and M. R. dos Santos e Passos Bueno
Product: Maestro MEA, Neural Module, CytoView MEA Plate,
Journal of Neuroinflammation, 26 July 2025
Publication
Coexistence of CN1A autoantibodies in GAD65 encephalitis exacerbates neurodegeneration
Author: A. Breuer, D. Kamalizade, T. Baumgartner, J. L. Berns, T. Opitz, F. S. Thaler, S. Schoch, L. Komorowski, C. Helmstaedter, R. Surges, A. J. Becker, and J. Pitsch
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Cell Reports, 22 July 2025
Publication
A hexamer tandem repeat RNA embedded within an SVA retrotransposon drives R-loop formation and neurodegeneration
Author: L. D’Ignazio, A. P.R. Lorenzetti, E. B. Penney, T. A. Evans, B. Qamar, A. E. McCord, A. S. Feltrin, A. R. Barbosa, B. J. Sheehan, B. Araujo, H. H. Giles, Y. Wang, T. Sawada, M. Zabolocki, M. Murcar, C. Fernandez-Cerado, G. P. Legarda, M. Sy, M. S. Velasco-Andrada, E. Munoz, M. C. Ang, C. C. E. Diesta, C. Bardy, D. C. Bragg, A. C.M. Paquola, and J. A. Erwin
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Translational Neurodegeneration, 03 June 2025
Publication
A genome-wide RNA interference screening reveals protectiveness of SNX5 knockdown in a Parkinson’s disease cell model
Author: M. Höllerhage, L. Duan, O. W. H. Chua, C. Moebius, S. H. Bothe, K. Losse, R. Kotzur, K. Lau, F. Hopfner, F. Richter, C. Wahl-Schott, M. Bickle, and G. U. Höglinger
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Molecular Neurodegeneration, 03 May 2025
Publication
Alzheimer’s disease protective allele of Clusterin modulates neuronal excitability through lipid-droplet-mediated neuron-glia communication
Author: X. Zhao, Y. Li, S. Zhang, A. Sudwarts, H. Zhang, A. Kozlova, M. J. Moulton, L. D. Goodman, Z. P. Pang, A. R. Sanders, H. J. Bellen, G. Thinakaran, and J. Duan
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Materials Today Bio Publication, 05 Feb 2024
Publication
Unraveling the assembloid: Real-time monitoring of dopaminergic neurites in an inter-organoid pathway connecting midbrain and striatal regions
Author: A. Ozgun, D. J. Lomboni, A. Aylsworth, A. Macdonald, W. A. Staines, M. Martina, M. G. Schlossmacher, J. S. Tauskela, J. Woulfe, and F. Variola
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
Neuron, 23 December 2024
Publication
A neurodegenerative cellular stress response linked to dark microglia and toxic lipid secretion
Author: A. Flury, L. Aljayousi, H. Park, M. Khakpour, J. Mechler, S. Aziz, J. D. McGrath, P. Deme, C. Sandberg, F. G. Ibáñez, O. Braniff, T. Ngo, S. Smith, M. Velez, D. M. Ramirez, D. Avnon-Klein, J. W. Murray, J. Liu, M. Parent, S. Mingote, N. J. Haughey, S. Werneburg, M. Tremblay, and P. Ayata
Product: Maestro Pro, CytoView MEA Plate, Neural Module,
Frontiers in Cellular Neuroscience, 24 October 2024
Publication
Neurovascular unit, neuroinflammation and neurodegeneration markers in brain disorders
Author: D. Kempuraj, K. D. Dourvetakis, J. Cohen, D. S. Valladares, R. S. Joshi, S. P. Kothuru, T. Anderson, B. Chinnappan, A. K. Cheema, N. G. Klimas, and T. C. Theoharides
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Molecular Neurodegeneration Publication, April 2024
Publication
Regulation of human microglial gene expression and function via RNAase-H active antisense oligonucleotides in vivo in Alzheimer’s disease
Author: L. Vandermeulen, I. Geric, L. Fumagalli, M. Kreir, A. Lu, A. Nonneman, J. Premereur, L. Wolfs, R. Policarpo, N. Fattorelli, A. De Bondt, I. Van Den Wyngaert, B. Asselbergh, M. Fiers, B. De Strooper, C. d’Ydewalle and R. Mancuso
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Translational Neurodegeneration Publication, 09 November 2023
Publication
Intranasal administration of induced pluripotent stem cell-derived cortical neural stem cell-secretome as a treatment option for Alzheimer’s disease
Author: H. Mo, J. Kim, J. Y. Kim, J. W. Kim, H. Han, S. H. Choi, Y. A. Rim and J. H. Ju
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ALS App Note
Application Note
Functional phenotypic characterization of precision reprogrammed human iPSC-derived disease models for ALS using high-throughput microelectrode arrays
Author: Charles River, Bit.Bio, Axion BioSystems
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Scientific Reports, 30 June 2023
Publication
The TNFR1 antagonist Atrosimab reduces neuronal loss, glial activation and memory deficits in an acute mouse model of neurodegeneration
Author: N. Ortí-Casañ, A. S. Boerema, K. Köpke, A. Ebskamp, J. Keijser, Y. Zhang, T. Chen, A. M. Dolga, K. Broersen, R. Fischer, K. Pfizenmaier, R. E. Kontermann and U. L. M. Eisel
Product: Maestro Edge, Neural Module, CytoView MEA Plate,
Alzheimer's Disease Publication Highlight
Flyer
Alzheimer’s Disease
Author: Axion BioSystems
Product: Maestro Pro, CytoView MEA Plate, Neural Module,
Publication Highlights April 2023
Flyer
Amyotrophic lateral sclerosis (ALS)
Author: Axion BioSystems
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
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Publication
Increased post-mitotic senescence in aged human neurons is a pathological feature of Alzheimer’s disease
Author: Herdy JR, Traxler L, Agarwal RK, Karbacher L, Schlachetzki JCM, Boehnke L, Zangwill D, Galasko D, Glass CK, Mertens J, Gage FH
Product: Neural Module,
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Publication
Lipid Accumulation Induced by APOE4 Impairs Microglial Surveillance of Neuronal-Network Activity
Author: Victor MB, Leary N, Luna X, Meharena HS, Bozzelli PL, Samaan G, Murdock MH, von Maydell D, Effenberger AH, Cerit O, Wen H-L, Liu L, Welch G, Bonner M, and Tsai L-H.
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Publication
Optimization of Long-Term Human iPSC-Derived Spinal Motor Neuron Culture Using a Dendritic Polyglycerol Amine-Based Substrate
Author: Thiry L, Clément JP, Haag R, Kennedy TE, and Stifani S.
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Publication
Edaravone activates the GDNF/RET neurotrophic signaling pathway and protects mRNA-induced motor neurons from iPS cells
Author: Li Q, Feng Y, Xue Y, Zhan X, Fu Y, Gui G, Zhou W, Richard JP, Taga A, Li P, Mao X, Maragakis NJ, Ying M.
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Cell Metabolism publication 2021 Aging skeletal muscle and brain and retina
Publication
Proteasome stress in skeletal muscle mounts a long-range protective response that delays retinal and brain aging
Author: Rai M, Coleman Z, Curley M, Nityanandam A, Platt A, Robles-Murguia M, Jiao, J, Finkelstein D, Wang Y-D, Xu B, Fan Y, Demontis F.
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2021 Rybak wolf brain organoids with herpes
Publication
Neurodegeneration in human brain organoids infected with herpes simplex virus type 1
Author: Rybak-Wolf A, Wyler E, Legnini I, Loewa A, Glažar P, Kim SJ, Pentimalli TM, Martinez AO, Beyersdorf B, Woehler A, Landthaler M and Rajewsky N.
Product: Maestro Pro, Neural Module, BioCircuit MEA Plate,