Resources
Journal of Neurochemistry, 18 August 2025
Publication
Ropinirole Functions Through a Dopamine Receptor D2-Independent Mechanism to Ameliorate Amyotrophic Lateral Sclerosis Phenotypes in TARDBP-Mutant iPSC-Derived Motor Neurons
Author: H. Asano, T. Kawaguchi, C. Kato, S. Morimoto, M. Yano, M. Minaguchi, D. Yasuda, K. Fukushima, and H. Okano
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
British Journal of Pharmacology, 13 February 2025
Publication
Novel FKBP prolyl isomerase 1A (FKBP12) ligand promotes functional improvement in SOD1G93A amyotrophic lateral sclerosis (ALS) mice
Author: L. Moreno-Martinez, N. Gaja-Capdevila, L. Mosqueira-Martín, M. Herrando-Grabulosa, L. Rodriguez-Gomez, K. Gonzalez-Imaz, A. C. Calvo, M. Sagartzazu-Aizpurua, L. Moreno-García, J. M. Fuentes, A. Acevedo-Arozena, J. M. Aizpurua, J. I. Miranda, A. L. de Munain, A. Vallejo-Illarramendi, X. Navarro, R. Osta, and F. J. Gil-Bea
Product: Maestro Edge, CytoView MEA Plate, Neural Module,
Axol Biosciences
Application Note
Multielectrode array characterization of human iPSC-derived motor neuron disease model for ALS drug discovery
Author: Axol Bioscience, Axion BioSystems
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
Cell Reports Publication, March 2024
Publication
Neuromuscular organoids model spinal neuromuscular pathologies in C9orf72 amyotrophic lateral sclerosis
Author: C. Gao, Q. Shi, X. Pan, J. Chen, Y. Zhang, J. Lang, S. Wen, X. Liu, T. L. Cheng, and K. Lei
Product: Maestro Edge, Neural Module, CytoView MEA Plate,
ALS App Note
Application Note
Functional phenotypic characterization of precision reprogrammed human iPSC-derived disease models for ALS using high-throughput microelectrode arrays
Author: Charles River, Bit.Bio, Axion BioSystems
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
Nature Communications Publication, 22 September 2023
Publication
C9orf72-ALS human iPSC microglia are pro-inflammatory and toxic to co-cultured motor neurons via MMP9
Author: B. F. Vahsen, S. Nalluru, G. R. Morgan, L. Farrimond, E. Carroll, Y. Xu, K. M. L. Cramb, B. Amein, J. Scaber, A. Katsikoudi, A. Candalija, M. Carcolé, R. Dafinca, A. M. Isaacs, R. Wade-Martins, E. Gray, M. R. Turner, S. A. Cowley and K. Talbot
Product: Maestro Edge, Neural Module, CytoView MEA Plate,
Stem Cell Reports, 17 August 2023
Publication
A novel protocol to derive cervical motor neurons from induced pluripotent stem cells for amyotrophic lateral sclerosis
Author: M. Yang, M. Liu, Y. F. Sánchez, S. Avazzadeh, L. R. Quinlan, G. Liu, Y. Lu, G. Yang, T. O'Brien, D. C. Henshall, O. Hardiman, and S. Shen
Product: Maestro Edge, Neural Module, CytoView MEA Plate,
NETRI & Axion Press Release
News
NETRI, in collaboration with Axion BioSystems, launches NeuroFluidics™ MEA line, high-throughput MEA-capable organs-on-chip
Author: NETRI
Product: Maestro Edge, Maestro Pro, Neural Module,
Publication Highlights April 2023
Flyer
Amyotrophic lateral sclerosis (ALS)
Author: Axion BioSystems
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
Biosensing system for drug evaluation of amyotrophic lateral sclerosis
Publication
Biosensing system for drug evaluation of amyotrophic lateral sclerosis based on muscle bundle and nano-biohybrid hydrogel composed of multiple motor neuron spheroids and carbon nanotubes
Author: T. Ha, S. Park, M. Shin, J-Y. Lee, J-H. Choi, J-W. Choi
Product: Maestro Edge, Neural Module, CytoView MEA Plate,
preview
Publication
Efficient generation of lower induced motor neurons by coupling Ngn2 expression with developmental cues
Author: F Limone, I Guerra San Juan, JM Mitchell, JLM Smith, K Raghunathan, D Meyer, S Dia Ghosh, A Couto, JR Klim, BJ Joseph, J Gold, CJ Mello, J Nemesh, BM Smith, M Verhage, SA McCarroll, O Pietiläinen, R Nehme, K Eggan
Product: Maestro Edge, Neural Module, CytoView MEA Plate,
preview image publication
Publication
Characterising the Function of iPSCs Using a Bioelectronic Assay
Author: Jim Ross, PhD
Product: Maestro Pro, Neural Module, Cardiac Module, Impedance Module,
Annals of Neurology, July 2022
Publication
Human Endogenous Retrovirus K Envelope in Spinal Fluid of Amyotrophic Lateral Sclerosis Is Toxic
Author: J. P. Steiner PhD, M. Bachani BS, N. Malik PhD, C. DeMarino PhD, W. Li PhD, K. Sampson MS, M. H. Lee PhD, J. Kowalak PhD, M. Bhaskar PhD, T. Doucet-O'Hare PhD, M. Garcia-Montojo PhD, M. Cowen MS, B. Smith MD, L. B. Reoma MD, J. Medina PhD, J. Brunel PhD, J. Pierquin PhD, B. Charvet PhD, H. Perron PhD, and A. Nath MD
Product: Maestro Edge, Neural Module, CytoView MEA Plate,
thumbnail of publication
Publication
TBK1 deficiency leads to TDP-43 pathology driven by endo-lysosomal dysfunction in human-induced motor neurons
Author: Hao, J.
Product: Maestro Edge, Neural Module, CytoView MEA Plate,
thumbnail of publication
Publication
Optimization of Long-Term Human iPSC-Derived Spinal Motor Neuron Culture Using a Dendritic Polyglycerol Amine-Based Substrate
Author: Thiry L, Clément JP, Haag R, Kennedy TE, and Stifani S.
Product: Maestro Edge, Neural Module, CytoView MEA Plate,
thumbnail of publication
Publication
Edaravone activates the GDNF/RET neurotrophic signaling pathway and protects mRNA-induced motor neurons from iPS cells
Author: Li Q, Feng Y, Xue Y, Zhan X, Fu Y, Gui G, Zhou W, Richard JP, Taga A, Li P, Mao X, Maragakis NJ, Ying M.
Product: Maestro Edge, Neural Module, CytoView MEA Plate,
Drug discovery World article on tuninig into the brain
News
Tuning in to the brain’s neural network
Author: Jim Ross, Ph.D.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
Lab and Life Scientist
News
Upgrading electrophysiology to take on ALS
Author: Jim Ross, Ph.D.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
Drug Discovery News
News
A mind for medicine
Author: Randall C. Willis
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
European Biopharmaceutical review
News
Probing Models of Neurological Disease in a Dish Using Multielectrode Arrays
Author: Jim Ross, Ph.D.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,