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Electrophysiological- and Neuropharmacological-Based Benchmarking of Human Induced Pluripotent Stem Cell-Derived and Primary Rodent Neurons
Author: Jezierski A, Baumann E, Aylsworth A, Costain WJ, Corluka S, Banderali U, Sodja C, Ribecco-Lutkiewicz M, Alasmar S, Martina M, and Tauskela JS.
Product: Maestro Edge, Neural Module, CytoView MEA Plate,
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A microRNA signature that correlates with cognition and is a target against cognitive decline
Author: Islam M, Kauran, L, Berulava T, Heilbronner U, Budde M, Centeno T, Elerdashvili V, Zafieriou M, Benito E, Sertel S, Goldberg M, Senner F, Kalman J, Burkhardt S, Oepen A, Sakib M, Kerimolgu C, Wirths O, Bickeböller H, Bartels C, Brosseron F, Buerger K, Cosma N, Fliessbach K, Heneka M, Janowitz D, Kilimann I, Kleinedam L, Laske C, Metzger C, Munk M, Perneczky R, Peters O, Priller J, Rauchmann B, Roy N, Schneider A, Spottke A, Spruth E, Teipel S, Tscheuschler M, Wagner M, Wiltfang J, Düzel E, Jessen F, Rizzoli S, Zimmermann W, Schulze T, Falkai P, Sananbenesi F and Fischer A.
Product: Neural Module, CytoView MEA Plate,
Technology Networks
News
Bioelectric Assay Identifies Potential COVID-19 Therapeutic Targets
Author: Christopher Basler, Ph.D.
Product: Maestro Z, Impedance Module, CytoView-Z Plate,
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Blebbistatin protects iPSC-CMs from hypercontraction and facilitates automated patch-clamp based electrophysiological study
Author: Li W, Luo X, Ulbricht Y, and Guan K.
Product: Maestro Edge, Cardiac Module, CytoView MEA Plate,
SPS 2021 Poster on MEA viability for neural and cardiac cytotoxicity
Poster
Multiplexed structure-function assay for high throughput drug safety testing on human induced pluripotent stem cell-derived cardiomyocytes and neurons
Author: Axion BioSystems
Product: Maestro Pro, MEA Viability Module, CytoView MEA Plate,
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Exercise as a model to identify microRNAs linked to human cognition: a role for microRNA-409 and microRNA-501
Author: Goldberg M, Islam MR, Kerimoglu C, Lancelin C, Gisa V, Burkhardt S, Krüger DM, Marquardt T, Malchow B, Schmitt A, Falkai P, Sananbenesi F, and Fischer A.
Product: Neural Module, Lumos MEA Plate, Lumos,
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Base Editing of Human Pluripotent Stem Cells for modeling Long QT syndrome
Author: Wu F, Guo T, Sun L, Li F, and Yang X.
Product: Maestro Edge, Cardiac Module, BioCircuit MEA Plate,
Drug discovery World article on tuninig into the brain
News
Tuning in to the brain’s neural network
Author: Jim Ross, Ph.D.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
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Exposure to nanoplastics impairs collective contractility of neonatal cardiomyocytes under electrical synchronization
Author: Roshanzadeh A, Oyunbaatar NE, Ganjbakhsh SE, Park S, Kim DS, Kanade PP, Lee S, Lee DW, and Kim ES.
Product: Maestro Edge, Cardiac Module, BioCircuit MEA Plate,
Covid and remdesivir treatment
Publication
Synthesis and antiviral activity of fatty acyl conjugates of remdesivir against severe acute respiratory syndrome coronavirus 2 and Ebola virus
Author: El-Sayed NS, Jureka AS, Edwards MR, Lohan S, Williams CG, Keiser PT, Davey RA, Totonchy J, Tiwari RK, Basler CF, and Parang K.
Product: Maestro Z, Impedance Module, CytoView-Z Plate,
Lab and Life Scientist
News
Upgrading electrophysiology to take on ALS
Author: Jim Ross, Ph.D.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
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News
Bioelectronic assays: Setting a standard for potency measurement
Author: Drug Discovery World, 2021
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Human Induced Pluripotent Stem Cell-Derived TDP-43 Mutant Neurons Exhibit Consistent Functional Phenotypes Across Multiple Gene Edited Lines Despite Transcriptomic and Splicing Discrepancies
Author: Smith AST, Chun C, Hesson J, Mathieu J, Valdmanis PN, Mack DL, Choi BO, Kim DH, and Bothwell M.
Product: Maestro Edge, Neural Module, CytoView MEA Plate,
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Effects of the Selective Serotonin Reuptake Inhibitor Fluoxetine on Developing Neural Circuits in a Model of the Human Fetal Cortex
Author: Tate K, Kirk B, Tseng A, Ulffers A, and Litwa K.
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Cnksr2 loss in mice leads to increased neural activity and behavioral phenotypes of Epilepsy-Aphasia Syndrome
Author: Erata E, Gao Y, Purkey AM, Soderblom EJ, McNamara JO, and Soderling SH.
Product: Maestro Edge, Neural Module, CytoView MEA Plate,
Drug Discovery News
News
A mind for medicine
Author: Randall C. Willis
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
Microglia on chimeric organoids
Publication
Human microglia states are conserved across experimental models and regulate neural stem cell responses in chimeric organoids
Author: Popova G, Soliman SS, Kim CN, Keefe MG, Hennick KM, Jain S, Li T, Tejera D, Shin D, Chhun BB, McGinnis CS, Speir M, Gartner ZJ, Mehta SB, Haeussler M, Hengen KB, Ransohoff RR, Piao X, Nowakowski TJ.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
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Influence of Janus Kinase Inhibitors on the Neuronal Activity as a Proof-of-Concept Model for Itch
Author: Wohlrab J, Stintzing D, Schultz L, Jügelt K, and Schroeder OH.
Product: Maestro Edge, Neural Module, CytoView MEA Plate,
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Rapid Makerspace Microfabrication and Characterization of 3D Microelectrode Arrays (3D MEAs) for Organ-on-a-Chip Models
Author: Didier CM, Kundu A, and Rajaraman S.
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European Biopharmaceutical review
News
Probing Models of Neurological Disease in a Dish Using Multielectrode Arrays
Author: Jim Ross, Ph.D.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,