Resources
Molecular Psychiatry, 30 August 2025
Publication
Effects of esketamine on electrophysiology and metabolic reprogramming in brain organoids: insights into antidepressant mechanisms
Author: M. Li, W. Duan, X. Hao, S. Li, C. Wang, Y. Liang, Z. Hu, D. Ma, M. Guo, C. Zuo, Z. Wang, Y. Feng, C. Hao, S. Qi, Y. Sun, M. Tang, C. Mao, K. Hashimoto, Y. Xu, J. Yuan, J. Yang, and C. Shi
Product: Maestro Edge, Neural Module, CytoView MEA Plate,
Translational Psychiatry, 29 August 2025
Publication
Altered development and network connectivity in a human neuronal model of 15q11.2 deletion-related neurodevelopmental disorders
Author: C. W. Habela, S. Liu, A. Taga, S. Oddoye, R. Dastgheyb, N. Haughey, D. E. Bergles, H. Song, G. Ming, and N. J. Maragakis
Product: Maestro Edge, Neural Module, CytoView MEA Plate,
Clinical and Translational Science, 23 August 2025
Publication
Delayed Repolarization Caused by hERG Block With Different Drug Modalities Can Be Detected in Stem Cell-Derived Cardiomyocytes: Incubation Time Matters
Author: Y. Qu, W. Guo, B. Wu, J. Cui, B. Gao, J. V. Nichols, and H. M. Vargas
Product: Maestro Pro,
Molecular Psychiatry, 22 August 2025
Publication
Differential effects of lithium on metabolic dysfunctions in astrocytes derived from bipolar disorder patients
Author: G. H. Baek, D. Kim, G. Son, H. Do, G. Yeon, M. Lee, M. Ji, J. Son, M. Ju, I. Ahn, C. S. Kang, H. Lee, S. Choi, J. M. Suh, J. Seo, F. H. Gage, M. Paik, Y. Park, D. Kim, and J. Han
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
Nature, 20 August 2025
Publication
Cancer-induced nerve injury promotes resistance to anti-PD-1 therapy
Author: E. N. Baruch, F. O. Gleber-Netto, P. Nagarajan, X. Rao, S. Akhter, T. Eichwald, T. Xie, M. Balood, A. Adewale, S. Naara, H. N. Sathishkumar, S. Islam, W. McCarthy, B. J. Mattson, R. Ferrarotto, M. K. Wong, M. A. Davies, S. Jindal, S. Basu, K. Roversi, A. Reza Nikpoor, M. Ahmadi, A. Ahmadi, C. Harwood, I. Leigh, D. Gong, P. Tallón de Lara, D. L. Tao, T. M. Davidson, N. J. Ajami, A. Futreal, K. Rai, V. Kochat, M. Castillo, P. Gunaratne, R. P. Goepfert, S. D. Hernandez, N. I. Khushalani, J. Wang, S. S. Watowich, G. A. Calin, M. R. Migden, M. Yuan, N. Liu, Y. Ye, W. L. Hwang, P. D. Vermeer, N. J. D’Silva, Y. L. Bunimovich, D. Yaniv, J. K. Burks, J. Gomez, P. M. Dougherty, K. Y. Tsai, J. P. Allison, P. Sharma, J. A. Wargo, J. N. Myers, S. Talbot, N. D. Gross, and M. Amit
Product: Maestro Edge, Neural Module, CytoView MEA Plate,
Scientific Reports, 20 August 2025
Publication
SNTA1-deficient human cardiomyocytes show shorter field potential duration and slower conduction velocity
Author: T. Dong, Y. Zhao, M. Zhang, W. Lang, D. Liu, K. Zhang, Y. Wang, L. Li, J. Lian, H. Yao, H. Zhang, H. Jin, T. Lu, L. Shen, L. Yue, and Y. Lin
Product: Maestro Edge, Cardiac Module, CytoView MEA Plate,
Nature Communications, 20 August 2025
Publication
Non-genetic neuromodulation with graphene optoelectronic actuators for disease models, stem cell maturation, and biohybrid robotics
Author: E. Molokanova, T. Zhou, P. Vasupal, V. P. Cherkas, P. Narute, M. S. A. Ferraz, M. Reiss, A. Almenar-Queralt, G. Chaldaiopoulou, J. Sena de Souza, H. Hemati, F. Downey, O. O. Olajide, C. T. Perez, F. Puppo, P. Mesci, S. L. Pfaff, D. Kireev, A. R. Muotri, and A. Savchenko
Product: Maestro Pro, Lumos, Neural Module, CytoView MEA Plate,
Molecular Psychiatry, 18 August 2025
Publication
Pathogenic microbiota disrupts the intact structure of cerebral organoids by altering energy metabolism
Author: M. Isik, C. C. Eylem, K. Erdogan-Gover, P. Aytar-Celik, B. M. Enuh, E. Emregul, A. Cabuk, Y. Yildirim, E. Nemutlu, A. R. Muotri, and B. Derkus
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
Molecular Therapy, 28 July 2025
Publication
Fetal rat neural progenitor cell transplantation after spinal cord injury improves motor recovery following optogenetic stimulation
Author: M. del Mar Sánchez-Martín, E. Giraldo, A. Alastrue-Agudo, E. López-Mocholi, S. Martín-Pérez, L. Maninno, G. Paniagua Soriano, A. I. F. Sánchez, J. Monreal-Trigo, J. M. Terrés-Haro, Q. V. Beneyto, A. Conesa, E. van Niekerk, M. Tuszynski, and V. Moreno-Manzano
Product: Maestro Edge, Neural Module, CytoView MEA Plate,
Scientific Reports, 13 August 2025
Publication
Functional discrimination of CSF from Alzheimer’s patients in a brain on chip platform
Author: L. Miny, J. Rontard, A. Allouche, N. Violle, L. Dubuisson, A. Batut, A. Ponomarenko, R. Talbi, H. Gautier, B. G. C. Maisonneuve, S. Roux, F. Larramendy, T. Honegger, and I. Quadrio
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
Scientific Reports, 12 August 2025
Publication
Morphological profiling reveals neuroprotection via mitochondrial uncoupling in human dopaminergic neurons
Author: V. Gorgogietas, A. Weiss, L. Cousin, D. Hoffmann, K. Schmitt, A. Ogier, P. A. Barbuti, B. F. R. Santos, I. Boussaad, A. Wittich, A. Zaliani, Ole Pless, R. Krüger, P. Sommer, and J. H. Wilbertz
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
Best Practices for in vitro neural assays on the Maestro MEA system
Application Note
Best practices for in vitro neural assays on the Maestro MEA system
Author: B. Streeter, D. Sullivan, and D. Millard
Product: Maestro Edge, Maestro Pro, Maestro Volt, Maestro MEA, Neural Module, CytoView MEA Plate,
Frontiers in Neuroscience, 27 July 2025
Publication
mTORC1-selective inhibitors rescue cellular phenotypes in TSC iPSC-derived neurons
Author: E. D. Buttermore, G. R. Srinivasan, H. Jumo, A. C. Swanson, B. O’Kelly, N. R. Makhortova, M. Sahin, and S. T. Tzannis
Product: Neural Module, CytoView MEA Plate,
Nature Neuroscience, 11 August 2025
Publication
Cross-species analysis of adult hippocampal neurogenesis reveals human-specific gene expression but convergent biological processes
Author: Y. Zhou, Y. Su, Q. Yang, J. Li, Y. Hong, T. Gao, Y. Zhong, X. Ma, M. Jin, X. Liu, N. Yuan, B. C. Kennedy, L. Wang, L. Yan, A. N. Viaene, I. Helbig, S. K. Kessler, J. E. Kleinman, T. M. Hyde, D. W. Nauen, C. Liu, Z. Liu, Z. Shen, C. Li, S. Xu, J. He, D. R. Weinberger, G. Ming, and H. Song
Product: Maestro Edge, Neural Module, CytoView MEA Plate,
EMBO Molecular Medicine, 5 August 2025
Publication
Convergent activation of the integrated stress response and ER–mitochondria uncoupling in VAPB-associated ALS
Author: C. Landry, J. P. Costanzo, M. Mitne-Neto, M. Zatz, A. E. Schaffer, M. Hatzoglou, A. R. Muotri, and H. C. Miranda
Product: Neural Module,
Scientific Reports, 05 August 2025
Publication
Transcriptome-based screening in TARDBP/TDP-43 knock-in motor neurons identifies the NEDD8-activating enzyme inhibitor MLN4924
Author: S. Lépine, G. Maussion, A. Schneider, A. Nauleau-Javaudin, M. J. Castellanos-Montiel, G. J. Ambriz, D. Spiegelman, N. Abdian, A. K. Franco-Flores, G. Haghi, L. Gursu, M. R. Fiorini, A. A. Dilliott, S. M. K. Farhan, M. Chaineau, and T. M. Durcan
Product: Maestro Edge, Neural Module, CytoView MEA Plate,
Maestro MEA: Optimized for Organoids
Video
Advancing Organoid Research Through MEA Innovation
Axion BioSystems
Product: Maestro Edge, Maestro Pro, Neural Module, MEA Creator Kit, Organoid MEA,
Science Advances, 30 July 2025
Publication
LARGE protein drives activity-induced homeostatic resetting
Author: B. A. Seo, H. Kim, C. C. Tuong, H. Kim, F. Dustov, S. Lee, S. Choi, and M. Kang
Product: Neural Module, CytoView MEA Plate,
Stem Cell Research & Therapy, 26 July 2025
Publication
NEXN deficiency leads to dilated cardiomyopathy in human pluripotent stem cell-derived cardiomyocytes
Author: M. Jiang, X. Chen, Y. Song, M. Wei, J. Cao, W. Lu, F. Lan, Y. Bai, and M. Cui
Product: Maestro Edge, Cardiac Module, CytoView MEA Plate,
Journal of Neuroinflammation, 26 July 2025
Publication
Coexistence of CN1A autoantibodies in GAD65 encephalitis exacerbates neurodegeneration
Author: A. Breuer, D. Kamalizade, T. Baumgartner, J. L. Berns, T. Opitz, F. S. Thaler, S. Schoch, L. Komorowski, C. Helmstaedter, R. Surges, A. J. Becker, and J. Pitsch
Product: Maestro Edge, Neural Module, CytoView MEA Plate,