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2017_jpharmacol_toxicolmethods_hyun_theassessmentofelectrophysiological.png
Publication
The assessment of electrophysiological activity in human-induced pluripotent stem cell-derived cardiomyocytes exposed to dimethyl sulfoxide and ethanol by manual patch clamp and multi-electrode array system
Author: Hyun SW, Kim BR, Hyun SA, Seo JW.
Product: Maestro Pro, Cardiac Module, Maestro Edge,
2017_toxicollett_kasteel_comparisonoftheacute.png
Publication
Comparison of the acute inhibitory effects of Tetrodotoxin (TTX) in rat and human neuronal networks for risk assessment purposes
Author: Kasteel EEJ, Westerink RH.
Product: Maestro Pro, Neural Module, Maestro Edge,
2017_stemcellreports_xu_reversalofphenotypicabnormalities.png
Publication
Reversal of Phenotypic Abnormalities by CRISPR/Cas9-Mediated Gene Correction in Huntington Disease Patient-Derived Induced Pluripotent Stem Cells
Author: Xu X, Tay Y, Sim B, Yoon SI, Huang Y, Ooi J, Utami KH, Ziaei A, Ng B, Radulescu C, Low D, Ng AY, Loh M, Venkatesh B, Ginhoux F, Augustine GJ, Pouladi MA.
Product: Maestro Pro, Neural Module, CytoView MEA Plate, Maestro Edge,
2017_cell_yissachar_anintestinalorganculture.png
Publication
An Intestinal Organ Culture System Uncovers a Role for the Nervous System in Microbe-Immune Crosstalk
Author: Yissachar N, Zhou Y, Ung L, Lai NY, Mohan JF, Ehrlicher A, Weitz DA, Kasper DL, Chiu IM, Mathis D, Benoist C.
Product: Maestro Pro, Maestro Edge,
2017_jcellsci_chiacchiaretta_neuronalhyperactivitycausesna.png
Publication
Neuronal hyperactivity causes Na+/H+ exchanger-induced extracellular acidification at active synapses
Author: Chiacchiaretta M, Latifi S, Bramini M, Fadda M, Fassio A, Benfenati F, Cesca F.
Product: Maestro Pro, Neural Module, CytoView MEA Plate, Maestro Edge,
2017_plosgenet_zhu_epilepsyassociatedgenenedd42.png
Publication
Epilepsy-associated gene Nedd4-2 mediates neuronal activity and seizure susceptibility through AMPA receptors
Author: Zhu J, Lee KY, Jewett KA, Man HY, Chung HJ, Tsai NP.
Product: Neural Module,
2017_jpharmacoltoxicolmethods_takasuna_comprehensiveinvitrocardiac.png
Publication
Comprehensive in vitro cardiac safety assessment using human stem cell technology: Overview of CSAHi HEART initiative
Author: Takasuna K, Asakura K, Araki S, Ando H, Kazusa K, Kitaguchi T, Kunimatsu T, Suzuki S, Miyamoto N.
Product: Maestro Pro, Cardiac Module, Maestro Edge,
2017_toxicolsci_blinova_comprehensivetranslationalassessmentof.png
Publication
Comprehensive Translational Assessment of Human Induced Pluripotent Stem Cell Derived Cardiomyocytes for Evaluating Drug-Induced Arrhythmias
Author: Blinova K, Stohlman J, Vicente J, Chan D, Johannesen L, Hortigon-Vinagre MP, Zamora V, Smith G, Crumb WJ, Pang L, Lyn-Cook B, Ross J, Brock M, Chvatal S, Millard D, Galeotti L, Stockbridge N, Strauss DG.
Product: Maestro Pro, Cardiac Module, Maestro Edge,
2016_neurotoxicology_dingemans_chronic14dayexposure.png
Publication
Chronic 14-day exposure to insecticides or methylmercury modulates neuronal activity in primary rat cortical cultures
Author: Dingemans MM, Schütte MG, Wiersma DM, de Groot A, van Kleef RG, Wijnolts FM, Westerink RH.
Product: Maestro Pro, Neural Module, Maestro Edge,
2016_stemcellderivedmodelsintoxicology_millard_thecipamicroelectrodearray.png
Publication
The CiPA Microelectrode Array Assay with hSC-Derived Cardiomyocytes: Current Protocol, Future Potential
Author: Millard DC, Clements M, Ross JD.
Product: Maestro Pro, Cardiac Module, Lumos MEA Plate, Lumos, Maestro Edge,
2016_altex_pamies_ahumanbrainmicrophysiological.png
Publication
A human brain microphysiological system derived from induced pluripotent stem cells to study neurological diseases and toxicity
Author: Pamies D, Barreras P, Block K, Makri G, Kumar A, Wiersma D, Smirnova L, Zhang C, Bressler J, Christian KM, Harris G, Ming GL, Berlinicke CJ, Kyro K, Song H, Pardo CA, Hartung T, Hogberg HT.
Product: Neural Module, Maestro Pro, Maestro Edge,
2016_toxicolsci_millard_identificationofdrugdrug.png
Publication
Identification of drug-drug interactions in vitro: a case study evaluating the effects of sofosbuvir and amiodarone on hiPSC-derived cardiomyocytes
Author: Millard DC, Strock CJ, Carlson CB, Aoyama N, Juhasz K, Goetze TA, Stoelzle-Feix S, Becker N, Fertig N, January CT, Anson BD, Ross JD.
Product: Maestro Pro, Cardiac Module, Maestro Edge,
2016_toxicolsci_brown_evaluationofamicroelectrode.png
Publication
Evaluation of a Microelectrode Array-Based Assay for Neural Network Ontogeny Using Training Set Chemicals
Author: Brown JP, Hall D, Frank CL, Wallace K, Mundy WR, Shafer TJ.
Product: Maestro Pro, Neural Module, Maestro Edge,
2016_stemcellreports_okubo_pretreatmentwithaysecretase.png
Publication
Pretreatment with a y-Secretase Inhibitor Prevents Tumor-like Overgrowth in Human iPSC-Derived Transplants for Spinal Cord Injury
Author: Okubo T, Iwanami A, Kohyama J, Itakura G, Kawabata S, Nishiyama Y, Sugai K, Ozaki M, Iida T, Matsubayashi K, Matsumoto M, Nakamura M, Okano H.
Product: Maestro Pro, Neural Module, CytoView MEA Plate, Maestro Edge,
2016_genomeres_mcsweeney_inhibitionofmicrorna128.png
Publication
Inhibition of microRNA 128 promotes excitability of cultured cortical neuronal networks
Author: McSweeney KM, Gussow AB, Bradrick SS, Dugger SA, Gelfman S, Wang Q, Petrovski S, Frankel WN, Boland MJ, Goldstein DB.
Product: Maestro Pro, Neural Module, CytoView MEA Plate, Maestro Edge,
2016_frontcellneurosci_galati_computersimulationssupporta.png
Publication
Computer simulations support a morphological contribution to BDNF enhancement of action potential generation
Author: Galati DF, Hiester BG, Jones KR.
Product: Neural Module,
2016_neuroscires_isoda_robustproductionofhuman.png
Publication
Robust production of human neural cells by establishing neuroepithelial-like stem cells from peripheral blood mononuclear cell-derived feeder-free iPSCs under xeno-free conditions
Author: Isoda M, Kohyama J, Iwanami A, Sanosaka T, Sugai K, Yamaguchi R, Matsumoto T, Nakamura M, Okano H.
Product: Maestro Pro, Neural Module, CytoView MEA Plate, Maestro Edge,
2016_dismodelmech_preininger_ahumanpluripotentstem.png
Publication
A human pluripotent stem cell model of catecholaminergic polymorphic ventricular tachycardia recapitulates patient-specific drug responses
Author: Preininger MK, Jha R, Maxwell JT, Wu Q, Singh M, Wang B, Dalal A, Mceachin ZT, Rossoll W, Hales CM, Fischbach PS, Wagner MB, Xu C.
Product: Cardiac Module,
2016_jpharmacoltoxicolmethods_cavero_comprehensiveinvitroproarrhythmia.png
Publication
Comprehensive in vitro Proarrhythmia Assay (CiPA): Pending issues for successful validation and implementation
Author: Cavero I, Guillon JM, Ballet V, Clements M, Gerbeau JF, Holzgrefe H.
Product: Maestro Pro, Cardiac Module, Maestro Edge,
2016_nature_chailangkarn_ahumanneurodevelopmentalmodel.png
Publication
A human neurodevelopmental model for Williams syndrome
Author: Chailangkarn T, Trujillo CA, Freitas BC, Hrvoj-Mihic B, Herai RH, Yu DX, Brown TT, Marchetto MC, Bardy C, McHenry L, Stefanacci L, Järvinen A, Searcy YM, DeWitt M, Wong W, Lai P, Ard MC, Hanson KL, Romero S, Jacobs B, Dale AM, Dai L, Korenberg JR, Gage FH, Bellugi U, Halgren E, Semendeferi K, Muotri AR.
Product: Maestro Pro, Neural Module, CytoView MEA Plate, Maestro Edge,