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2018_toxicolsci_millard_crosssitereliabilityof.png
Publication
Cross-site reliability of human induced pluripotent stem-cell derived cardiomyocyte based safety assays using microelectrode arrays: Results from a blinded CiPA Pilot Study
Author: Millard D, Dang Q, Shi H, Zhang X, Strock C, Kraushaar U, Zeng H, Levesque P, Lu HR, Guillon JM, Wu JC, Li Y, Luerman G, Anson B, Guo L, Clements M, Abassi YA, Ross J, Pierson J, Gintant G.
Product: Maestro Pro, Maestro Edge, Cardiac Module,
2018_jove_sanchez_assessmentoftheeffects.png
Publication
Assessment of the effects of endocrine disrupting compounds on the development of vertebrate neural network function using multi-electrode arrays
Author: Sanchez KR, Mersha MD, Dhillon HS, Temburni MK.
Product: Neural Module,
2018_cerebralcortex_valente_constitutiveinactivationofthe.png
Publication
Constitutive inactivation of the PRRT2 gene alters short-term synaptic plasticity and promotes network hyperexcitability in hippocampal neurons
Author: Valente P, Romei A, Fadda M, Sterlini B, Lonardoni D, Forte N, Fruscione F, Castroflorio E, Michetti C, Giansante G, Valtorta F, Tsai JW, Zara F, Nieus T, Corradi A, Fassio A, Baldelli P, Benfenati F.
Product: Neural Module, Maestro Pro, Maestro Edge,
2018_cellstemcell_rajamani_superobesepatientderived.png
Publication
Super-obese patient-derived iPSC hypothalamic neurons exhibit obesogenic signatures and hormone responses
Author: Rajamani U, Gross AR, Hjelm BE, Sequeira A, Vawter MP, Tang J, Gangalapudi V, Wang Y, Andres AM, Gottlieb RA, Sareen D.
Product: Neural Module, Maestro Pro, Maestro Edge,
2018_toxicolapplpharmacol_kreir_doinvitroassays.png
Publication
Do in vitro assays in rat primary neurons predict drug-induced seizure liability in humans?
Author: Kreir M, Van Deuren B, Versweyveld S, De Bondt A, Van den Wyngaert I, Van der Linde H, Lu HR, Teuns G, Gallacher DJ.
Product: Neural Module, Maestro Pro, Maestro Edge,
2018_neurotoxicology_zwartsen_neurotoxicityscreeningofnew.png
Publication
Neurotoxicity screening of new psychoactive substances (NPS): effects on neuronal activity in rat cortical cultures using microelectrode arrays (MEA)
Author: Zwartsen A, Hondebrink L, Westerink RHS.
Product: Neural Module, Maestro Pro, Maestro Edge,
2018_brain_fruscione_prrt2controlsneuronalexcitability.png
Publication
PRRT2 controls neuronal excitability by negatively modulating Na+ channel 1.2/1.6 activity
Author: Fruscione F, Valente P, Sterlini B, Romei A, Baldassari S, Fadda M, Prestigio C, Giansante G, Sartorelli J, Rossi P, Rubio A, Gambardella A, Nieus T, Broccoli V, Fassio A, Baldelli P, Corradi A, Zara F, Benfenati F.
Product: Neural Module, Maestro Pro, Maestro Edge, CytoView MEA Plate,
2018_cellstemcell_ziller_dissectingthefunctionalconsequences.png
Publication
Dissecting the functional consequences of de novo DNA methylation dynamics in human motor neuron differentiation and physiology
Author: Ziller MJ, Ortega JA, Quinlan KA, Santos DP, Gu H, Martin EJ, Galonska C, Pop R, Maidl S, Di Pardo A, Huang M, Meltzer HY, Gnirke A, Heckman CJ, Meissner A, Kiskinis E.
Product: Neural Module, Maestro Pro, Maestro Edge,
(2018) Bradley et al. In Vitro Screening for Seizure Liability Using Microelectrode Array Technology
Publication
In vitro screening for seizure liability using microelectrode array technology
Author: Bradley JA, Luithardt HH, Metea MR, Strock CJ.
Product: Neural Module, Maestro Pro, Maestro Edge,
2018_cell_liu_rescueoffragilexsyndrome.png
Publication
Rescue of Fragile X Syndrome neurons by DNA methylation editing of the FMR1 gene
Author: Liu XS, Wu H, Krzisch M, Wu X, Graef J, Muffat J, Hnisz D, Li CH, Yuan B, Xu C, Li Y, Vershkov D, Cacace A, Young RA, Jaenisch R.
Product: Maestro Pro, Maestro Edge, Cardiac Module,
2018_jpharmacoltoxicolmethods_kopljar_impactofcalciumsensitive.png
Publication
Impact of calcium-sensitive dyes on the beating properties and pharmacological responses of human iPS-derived cardiomyocytes using the calcium transient assay
Author: Kopljar I, Hermans AN, Teisman A, Gallacher DJ, Lu HR.
Product: Maestro Pro, Cardiac Module, Maestro Edge,
2018_toxicolapplpharmacol_frank_definingtoxicologicaltippingpoints.png
Publication
Defining toxicological tipping points in neuronal network development
Author: Frank CL, Brown JP, Wallace K, Wambaugh JF, Shah I, Shafer TJ.
Product: Neural Module, Maestro Pro, Maestro Edge,
2018_jpharmacoltoxicolmethods_mulder_predictingcardiacsafetyusing.png
Publication
Predicting cardiac safety using human induced pluripotent stem cell-derived cardiomyocytes combined with multi-electrode array (MEA) technology: A conference report
Author: Mulder P, de Korte T, Dragicevic E, Kraushaar U, Printemps R, Vlaming MLH, Braam SR, Valentin JP.
Product: Maestro Pro, Maestro Edge, Cardiac Module,
2018_trendspharmacolsci_yang_nav17asapharmacogenomic.png
Publication
NaV1.7 as a pharmacogenomic target for pain: Moving toward precision medicine
Author: Yang Y, Mis MA, Estacion M, Dib-Hajj SD, Waxman SG.
Product: Neural Module, Maestro Pro, Maestro Edge,
2018_natcommun_blake_staphylococcusaureusproducespain.png
Publication
Staphylococcus aureus produces pain through pore-forming toxins and neuronal TRPV1 that is silenced by QX-314
Author: Blake KJ, Baral P, Voisin T, Lubkin A, Pinho-Ribeiro FA, Adams KL, Roberson DP, Ma YC, Otto M, Woolf CJ, Torres VJ, Chiu IM.
Product: Neural Module,
2017_jpharmacoltoxicolmethods_hyn_theeffectsofgentamicin.png
Publication
The effects of gentamicin and penicillin/streptomycin on the electrophysiology of human induced pluripotent stem cell-derived cardiomyocytes in manual patch clamp and multi-electrode array system
Author: Hyun SW, Kim BR, Lin D, Hyun SA, Yoon SS, Seo JW.
Product: Maestro Pro, Cardiac Module, Maestro Edge,
2017_plosone_jensen_effectsofgabacrand.png
Publication
Effects of GABACR and mGluR1 antagonists on contrast response functions of Sprague-Dawley and P23H rat retinal ganglion cells
Author: Jensen R.
Product: Neural Module,
2017_jneurochem_gupta_fibroblastgrowthfactor2.png
Publication
Fibroblast Growth Factor 2 regulates activity and gene expression of human postmitotic Excitatory Neurons
Author: Gupta S, M-Redmond T, Meng F, Tidball A, Akil H, Watson S, Parent JM, Uhler M.
Product: Maestro Pro, Neural Module, Maestro Edge,
2017_jpharmacoltoxicolmethods_schocken_comparativeanalysisofmedia.png
Publication
Comparative analysis of media effects on human induced pluripotent stem cell-derived cardiomyocytes in Proarrhythmia risk assessment
Author: Schocken D, Stohlman J, Vicente J, Chan D, Patel D, Matta MK, Patel V, Brock M, Millard D, Ross J, Strauss DG, Blinova K.
Product: Maestro Pro, Cardiac Module, Maestro Edge,
2017_acsbiomaterscieng_edwards_thecomparisonofnmda.png
Publication
The comparison of NMDA and AMPA channel expression and function between embryonic and adult neurons utilizing microelectrode array systems
Author: Edwards D, Sommerhage F, Berry B, Nummer H, Raquet M, Clymer B, Stancescu M, Hickman JJ.
Product: Neural Module,