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An Optimized Workflow to Generate and Characterize iPSC-Derived Motor Neuron (MN) Spheroids
Publication
An Optimized Workflow to Generate and Characterize iPSC-Derived Motor Neuron (MN) Spheroids
Author: María José Castellanos-Montiel , Mathilde Chaineau , Anna Kristyna Franco-Flores, Ghazal Haghi,
Dulce Carrillo-Valenzuela, Wolfgang E. Reintsch , Carol X.-Q. Chen and Thomas M. Durcan
Product:
Kv7-specific activators
Publication
Kv7-specific activators hyperpolarize resting membrane potential and modulate human iPSC-derived sensory neuron excitability
Author: Mark Estacion, Shujun Liu, Xiaoyang Cheng, Sulayman Dib-Hajj, and Stephen G. Waxman
Product:
Injectable Contraceptive
Publication
Injectable Contraceptive, Depo-Provera, Produces Erratic Beating Patterns in Patient-Specific Induced Pluripotent Stem Cell-derived Cardiomyocytes with Type 2 Long QT Syndrome
Author: Pinsky AM, Gao X, Bains S, Kim CSJ, Louradour J, Odening KE, Tester DJ, Giudicessi JR, Ackerman MJ
Product: Maestro Edge, Cardiac Module, BioCircuit MEA Plate,
Biosensing system for drug evaluation of amyotrophic lateral sclerosis
Publication
Biosensing system for drug evaluation of amyotrophic lateral sclerosis based on muscle bundle and nano-biohybrid hydrogel composed of multiple motor neuron spheroids and carbon nanotubes
Author: T. Ha, S. Park, M. Shin, J-Y. Lee, J-H. Choi, J-W. Choi
Product: Maestro Edge, Neural Module, CytoView MEA Plate,
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Publication
Natural variation in gene expression and viral susceptibility revealed by neural progenitor cell villages
Author: MF Wells, J Nemesh, S Ghosh, JM Mitchell, MR Salick, CJ Mello, D Meyer, O Pietilainen, F Piccioni, EJ Guss, K Raghunathan, M Tegtmeyer, D Hawes, A Neumann, KA Worringer, S Kommineni, K Chan, BK Peterson, JJ Raymond, SA McCarroll
Product: Neural Module, CytoView MEA Plate,
Sophoridine manifests as a leading compound for anti-arrhythmia with multiple ion-channel blocking effects
Publication
Sophoridine manifests as a leading compound for anti-arrhythmia with multiple ion-channel blocking effects
Author: T Song, Y Hao, M Wang, T Li, C Zhao, J Li, Y Hou
Product: Maestro Edge, Cardiac Module, BioCircuit MEA Plate,
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Publication
Selective inhibition of excitatory synaptic transmission alters the emergent bursting dynamics of in vitro neural networks
Author: JS Weir, N Christiansen, A Sandvig, I Sandvig
Product: Maestro Pro,
JNP March 2023 Publication
Publication
Nicolaioidesin C: An Antiausterity Agent Shows Promising Antitumor Activity in a Pancreatic Cancer Xenograft Mouse Model
Author: N. Duy Phan, A. M. Omar, I. Takahashi, H. Baba, T. Okumura, J. Imura, T. Okada, N. Toyooka, T. Fujii, and S. Awale
Product: Lux, Scratch Assay Module,
2023 Frontiers in immunology aerosolized nicotine from e-cigarettes
Publication
Aerosolized nicotine from e-cigarettes alters gene expression, increase lung protein permeability, and impairs viral clearance in murine influenza infection
Author: Maishan, M., Sarma, A., Chun, L.F., Caldera., S., Fang, X., Abbott, J., Christenson, S.A., Langelier, C.R., Calfee, C.S., Gotts, J.E and Matthay, M.A.
Product: Exact FL, Cell Counting Module,
Scientists use Axion’s noninvasive, label-free Maestro MEA to monitor the electrophysiological properties of cardiomyocytes in vitro.
Publication
Comparative analysis of the cardiomyocyte differentiation potential of induced pluripotent stem cells reprogrammed from human atrial or ventricular fibroblasts
Author: Lu Wang, Thanh Nguyen, Manuel Rosa-Garrido, Yang Zhou, David C. Cleveland and Jianyi Zhang

Frontiers In Bioengineering and Biotechnology, 10 February 2023
Product: Maestro Edge, Cardiac Module, BioCircuit MEA Plate,
PNAS Publication March 9, 2023
Publication
Visualizing cell–cell communication using synthetic notch activated MRI
Author: T. Wang, Y. Chen, N. Nystrom, S. Liu, Y. Fu, F. Martinez, T. Scholl, and J. Ronald
Product: Lux,
Label-free in vitro assays predict the potency of anti-disialoganglioside chimeric antigen receptor T-cell products
Publication
Label-free in vitro assays predict the potency of anti-disialoganglioside chimeric antigen receptor T-cell products
Author: M Logun, MB Colonna , KP Mueller, D Ventarapragada, R Rodier, C Tondepu, NJ Piscopo, A Das, S Chvatal, HB Hayes, CM Capitini, DJ Brat, T Kotanchek, AS Edison, K Saha, L Karumbaiah
Product: Maestro Z, Impedance Module,
Enterovirus D-68 Infection of Primary Rat Cortical Neurons
Publication
Enterovirus D-68 Infection of Primary Rat Cortical Neurons: Entry, Replication, and Functional Consequences
Author: Katrien C. K. Poelaerta, Regina G. D. M. van Kleefb, Mengying Liua, Arno van Vlieta, Heyrhyoung Lyooa, Lora-Sophie Gerberb, Yoshiki Narimatsuc, Christian Büllc, Henrik Clausenc, Erik de Vriesa, Remco H. S. Westerinkb, Frank J. M. van Kuppevelda

Product: Neural Module, CytoView MEA Plate,
Royal Society of Chemistry Publication March 2023
Publication
Application of under-oil open microfluidic systems for rapid phenotypic antimicrobial susceptibility testing
Author: C. Li, S. McCrone, J. Warrick, D. Andes, Z. Hite, C. Volk, W. Rose and D. Beebe
Product: Omni, Confluency Module,
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Publication
Directed differentiation of human hindbrain neuroepithelial stem cells recapitulates cerebellar granule neurogenesis
Author: BM Dave, X Chen, F McCready, JK Tailor, J Ellis, X Huang, PB Dirks

Product: CytoView MEA Plate, Neural Module,
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Publication
Diverging Parkinson’s Disease Pathology between patient-derived GBAN370S, LRRK2G2019S and engineered SNCAA53T iPSC-derived Dopaminergic Neurons
Author: A Fathi, K Bakshy, L Zieghami, R Fiene, R Bradley, S Dickerson, C Carlson, S Schachtele, J Liu
Product: Neural Module, Maestro Pro,
2023 Frontiers in neuroscience Selective inhibition of excitatory synaptic transmission
Publication
Selective inhibition of excitatory synaptic transmission alters the emergent bursting dynamics of in vitro neural networks
Author: Weir JS, Christiansen N, Sandvig A and Sandvig I.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
molecules, 15 February 2023
Publication
Functionalized sulfur-containing heterocyclic analogs induce Sub-G1 arrest and apoptotic cell death of laryngeal carcinoma in vitro
Author: B. Haridevamuthu, T. Manjunathan, C. R. W. Alphonse, R. S. Kumar, S. Thanigaivel, S. C. Kishore, V. Sundaram, P. Gopinath, Jesu Arockiaraj, and S. Bellucci
Product: Lux,
Scientists use Axion’s Maestro platform to investigate the role of MYT1L in autism spectrum disorders in vitro and uncover potential new therapeutic pathways.
Publication
MYT1L haploinsufficiency in human neurons and mice causes autism-associated phenotypes that can be reversed by genetic and pharmacologic intervention
Author: Bettina Weigel, Jana F. Tegethoff, Sarah D. Grieder, Bryce Lim, Bhuvaneswari Nagarajan, Yu-Chao Liu,
Jule Truberg, Dimitris Papageorgiou, Juan M. Adrian-Segarra, Laura K. Schmidt, Janina Kaspar, Eric Poisel,
Elisa Heinzelmann, Manu Saraswat, Marleen Christ, Christian Arnold, Ignacio L. Ibarra, Joaquin Campos,
Jeroen Krijgsveld, Hannah Monyer, Judith B. Zaugg, Claudio Acuna and Moritz Mall
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
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Publication
A Robust Pipeline for the Multi-Stage Accelerated Differentiation of Functional 3D Cortical Organoids from Human Pluripotent Stem Cells
Author: D Whye, D Wood, WA Saber, EM Norabuena, NR Makhortova, M Sahin, ED Buttermore
Product: Maestro Pro,