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ER stress-induced modulation of neural activity and seizure susceptibility is impaired in a fragile X syndrome mouse model
Author: Authors: Liu D-C, Lee KY, Lizarazo S, Cook JK, and Tsai N-P.
Product: Neural Module, CytoView MEA Plate,
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Application of in vitro data in physiologically-based kinetic models for quantitative in vitro-in vivo extrapolation: A case-study for baclofen
Author: Kasteel EEJ, Lautz LS, Culot M, Kramer NI, and Zwartsen A.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
Summa Equity and Axion
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Summa Equity acquires Axion BioSystems
Author: Summa Equity and Axion BioSystems
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2021 Yang publication on nocioceptive response to buffers
Publication
Multi-Electrode Array of Sensory Neurons as an In Vitro Platform to Identify the Nociceptive Response to Pharmaceutical Buffer Systems of Injectable Biologics
Author: Eaton M, Que Z, Zhang J, Beck K, Shi R, McDermott J, Ladisch M, and Yang Y.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
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Bisphenol S and bisphenol F are less disruptive to cardiac electrophysiology, as compared to bisphenol A
Author: Prudencio TM, Swift LM, Guerrelli D, Cooper B, Reilly M, Ciccarelli N, Sheng J, Jaimes R, and Posnack NG.
Product: Maestro Pro, Cardiac Module, CytoView MEA Plate,
Manu platt webinar on sickle cell disease and using the Maestro Z for barrier integrity analysis
Coffee Break Webinar
Sickle cell anemia - Studying inflammation mediated vascular permeability
Author: Dr. Manu Platt
Product: Maestro Z, CytoView-Z Plate, Impedance Module, Maestro ZHT,
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Investigating inherited arrhythmias using hiPSC-derived cardiomyocytes
Author: Arslanova A, Shafaattalab S, Lin E, Barszczewski T, Hove-Madsen L, and Tibbits GF.
Product: Maestro Pro, Cardiac Module, CytoView MEA Plate,
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An Electrophysiological and Pharmacological Study of the Properties of Human iPSC-Derived Neurons for Drug Discovery
Author: Halliwell RF, Salmanzadeh H, Coyne L, and Cao WS.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
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Maternal Bisphenol A (BPA) Exposure Alters Cerebral Cortical Morphogenesis and Synaptic Function in Mice
Author: Lee CY, Hyun S-A, Ko MY, Kim HR, Rho J, Kim KK, Kim W-Y, Ka M.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
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Pharmacogenomic approach to cure the pain of the 'burning man'
Author: Dr Yang Yang
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
ISSCR 2021 Innovation showcase video
Video
ISSCR 2021: Neural activity in a dish: Advancing our understanding of nervous system disorders
Evangelos Kiskinis, Ph.D. and David Belair, Ph.D.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
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Culture of Rat Primary Cortical Cells for Microelectrode Array (MEA) Recordings to Screen for Acute and Developmental Neurotoxicity
Author: Gerber L-S, van Melis LVJ, van Kleef RGDM, de Groot A, and Westerink RHS.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
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Publication
Using the dCas9-KRAB system to repress gene expression in hiPSC-derived NGN2 neurons
Author: Li A, Cartwright S, Yu A, Ho Seok-Man, Schrode N, Deans PJM, Matos MR, Garcia MF, Townsley KG, Zhang B, and Brennand KJ.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
2021 publication nature using induced pluripotent stem cells to investigate human neuronal phenotypes in 1q21.1 deletion
Publication
Using induced pluripotent stem cells to investigate human neuronal phenotypes in 1q21.1 deletion and duplication syndrome
Author: Chapman G, Alsaqati M, Lunn S, Singh T, Linden SF, Linden DEJ, van den Bree MBM, Ziller M, Owen MJ, Hall J, Harwood AJ and Syed YA.
Product: Maestro Pro, CytoView MEA Plate, Neural Module,
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Measuring Real-Time Cell Therapy Potency With Bioelectronic Assays
Author: Jim Ross, PhD
Product: Maestro Pro, Maestro Z, Impedance Module, Maestro Edge, Maestro ZHT, GxP Impedance Module,
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Human amyotrophic lateral sclerosis excitability phenotype screen: Target discovery and validation
Author: Huang X, Roet KCD, Zhang L, Brault A, Berg AP, Jefferson AB, Klug-McLeod J, Leach KL, Vincent F, Yang H, Coyle AJ, Jones LH, Frost D, Wiskow O, Chen K, Maeda R, Grantham A, Dornon MK, Klim JR, Siekmann MT, Zhao D, Lee S, Eggan K, and Woolf CJ.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
ISSCR 2021 poster - Axion BioSystems
Poster
Characterization of an in vitro synaptic propagation assay using iPSC-derived neurons and multiwell MEA technology
Author: Daniel Millard, Denise Sullivan, Heather Hayes
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
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[PRE-PRINT] Gain-of-function cardiomyopathic mutations in RBM20 rewire splicing regulation and re-distribute ribonucleoprotein granules within processing bodies
Author: Fenix AM, Miyaoka Y, Bertero A, Blue S, Spindler MJ, Tan KKB, Perez-Bermejo J, Chan AH, Mayer SJ, Nguyen T, Russell CR, Lizarraga P, Truong A, So P-L, Kulkarni A, Chetal K, Sathe S, Sniadecki NJ, Yeo GW, Murry CE, Conklin BR, and Salomonis N.
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A peptide encoded within a 5′ untranslated region promotes pain sensitization in mice
Author: Barragan-Iglesias P, Kunder N, Wanghzou A, Black B, Ray PR, Lou TF, Bryan de la Peña J, Atmaramani R, Shukla T, Pancrazio JJ, Price TJ, and Campbell ZT.
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Two independent mouse lines carrying the Nav1.7 I228M gain-of-function variant display dorsal root ganglion neuron hyperexcitability but a minimal pain phenotype
Author: Chen L, Wimalasena NK, Shim J, Han C, Lee SI, Gonzalez-Cano R, Estacion M, Faber CG, Lauria G, Dib-Hajj SD, Woolf CJ, and Waxman SG.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,