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Dysfunction of striatal MeCP2 is associated with cognitive decline in a mouse model of Alzheimer’s disease
Author: Lee S, Kim TK, Choi JE, Choi Y, You M, Ryu J, Chun YL, Ham S, Hyeon SJ, Ryu H, Kim H-S, and Im H-I.
Product: Maestro Edge, Neural Module, CytoView MEA Plate,
2022 Journal of Medical Chemistry
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Discovery of Novel Sphingosine-1-Phosphate-1 Receptor Agonists for the Treatment of Multiple Sclerosis
Author: Park SJ, Yeon SK, Kim Y, Kim HJ, Kim S, Kim J, Choi JW, Kim B, Lee EH, Kim R, Seo SH, Lee J, Kim JW, Lee H-Y, Hwang H, Bahn Y-S, Cheong E, Park J-H, and Park KD.
Product: Maestro Pro, Cardiac Module, CytoView MEA Plate,
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Functional Characterization of Human Pluripotent Stem Cell-Derived Models of the Brain with Microelectrode Arrays
Author: Pelkonen A, Pistono C, Klecki P, Gómez-Budia M, Dougalis A, Kontinnen H, Stanová I, Fagerlund I, Leinonen V, Korhonen P, and Malm T.
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Impact of High-Dose Irradiation on Human iPSC-Derived Cardiomyocytes Using Multi-Electrode Arrays: Implications for the Antiarrhythmic Effects of Cardiac Radioablation
Author: Kim JS, Choi SW, Park Y-G, Jim SJ, Choi CH, Cha M-J, and Chang JH.
Product: Maestro Edge, Cardiac Module, BioCircuit MEA Plate,
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FTH promotes the proliferation and renders the HCC cells specifically resist to ferroptosis by maintaining iron homeostasis
Author: Hu W, Zhou C, Jing Q, Li Y, Yang J, Yang C, Wang L, Hu J, Li H, Wang H, Yuan C, Zhou Y, Ren X, Tong X, Du J, and Wang Y.
Product: Maestro Z, Impedance Module, CytoView-Z Plate,
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Using hiPSC-CMs to Examine Mechanisms of Catecholaminergic Polymorphic Ventricular Tachycardia
Author: Arslanova A, Shafaattalab S, Ye K, Asghari P, Lin L, Kim B, Roston TM, Hove-Madsen L, Van Petegem F, Sanatani S, Moore E, Lynn F, Søndergaard M, Luo Y, Chen SRW, and Tibbits GF.
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Junctional instability in neuroepithelium and network hyperexcitability in a focal cortical dysplasia human model
Author: Avansini SH, Puppo F, Adams JW, Vieira AS, Coan AC, Rogerio F, Torres FR, Araújo PAOR, Martin M, Montenegro MA, Yasuda CL, Tedeschi H, Ghizoni E, França AFEC, Alvim MKM, Athié MC, Rocha CS, Almeida VS, Dias EV, Delay L, Molina E, Yaksh TL, Cendes F, Lopes Cendes I, and Muotri AR.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
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HDAC6 Inhibition Corrects Electrophysiological and Axonal Transport Deficits in a Human Stem Cell-Based Model of Charcot-Marie-Tooth Disease (Type 2D)
Author: Smith AST, Kim JH, Chun C, Gharai A, Moon HW, Kim EY, Nam SH, Ha N, Song JY, Chung KW, Doo HM, Hesson J, Mathieu J, Bothwell M, Choi BO, and Kim DH.
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E3 ubiquitin ligase Nedd4-2 exerts neuroprotective effects during endoplasmic reticulum stress
Author: Lodes DE, Zhu J, and Tsai N-P.
Product: Neural Module,
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Integrated Omic Analyses Identify Pathways and Transcriptomic Regulators Associated with Chemical Alterations of in Vitro Neural Network Formation
Author: Marable CA, Frank CL, Seim RF, Hester S, Henderson WM, Chorley B, and Shafer TJ.
Product: Maestro Edge, Neural Module, CytoView MEA Plate,
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Human Spinal Organoid-on-a-Chip to Model Nociceptive Circuitry for Pain Therapeutics Discovery
Author: Ao Z, Cai H, Wu Z, Krzesniak J, Tian C, Lai YY, Mackie K, and Guo F.
Product: Maestro Edge, Neural Module, CytoView MEA Plate,
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Assessment of cerebral spinal fluid biomarkers and microRNA-mediated disease mechanisms in spinal muscular atrophy patient samples
Author: Welby E, Rehborg RJ, Harmelink M, and Ebert AD.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
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Shed CNTNAP2 ectodomain is detectable in CSF and regulates Ca2+ homeostasis and network synchrony via PMCA2/ATP2B2
Author: Martín-de-Saavedra MD, Dos Santos M, Culotta L, Varea O, Spielman BP, Parnell E, Forrest MP, Gao R, Yoon S, McCoig E, Jalloul HA, Myczek K, Khalatyan N, Hall EA, Turk LS, Sanz-Clemente A, Comoletti D, Lichtenthaler SF, Burgdorf JS, Barbolina MV, Savas JN, Penzes P.
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Phenotypic Variability in iPSC-Induced Cardiomyocytes and Cardiac Fibroblasts Carrying Diverse LMNA Mutations
Author: Yang J, Argenziano MA, Burgos Angulo M, Bertalovitz A, Beidokhti MN, and McDonald TV.
Product: Maestro Edge, Cardiac Module, CytoView MEA Plate,
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The Linkage Phase of the Polymorphism KCNH2-K897T Influences the Electrophysiological Phenotype in hiPSC Models of LQT2
Author: van den Brink L, Brandão KO, Yiangou L, Blanch-Asensio A, Mol MPH, Mummery CL, Verkerk AO, and Davis RP.
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Bacterial neurotoxic metabolites in multiple sclerosis cerebrospinal fluid and plasma
Author: Ntranos A, Park HJ, Wentling M, Tolstikov V, Amatruda M, Inbar B, Kim-Schulze S, Frazier C, Button J, Kiebish MA, Lublin F, Edwards K, and Casaccia P.
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(preprint) STRAIGHT-IN: A platform for high-throughput targeting of large DNA payloads into human pluripotent stem cells
Author: Grandela C, Blanch-Asensio A, Brandão KO, de Korte T, Yiangou L, Mol MPH, van Meer BJ, Mummery CL, and Davis RP.
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COVID-19 Therapeutic Discovery Using a Bioelectronic Assay
Author: James Ross, PhD
Product: Maestro Z, Impedance Module, CytoView-Z Plate,
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16pdel lipid changes in iPSC-derived neurons and function of FAM57B in lipid metabolism and synaptogenesis
Author: Tomasello DL, Kim JL, Khodour Y, McCammon JM, Mitalipova M, Jaenisch R, Futerman AH, and Sive H.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
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Activation of retinal ganglion cells using a biomimetic artificial retina
Author: Greco JA, Wagner NL, Jensen RJ, Lawrence DB, Ranaghan MJ, Sandberg MN, Sandberg DJ, and Birge RR.
Product: Neural Module,