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News
Axion BioSystems’ Lumos™ Announced as “Top 10 Innovation of 2016”
Author: Axion BioSystems
Product: Lumos, Lumos MEA Plate,
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Publication
The CiPA Microelectrode Array Assay with hSC-Derived Cardiomyocytes: Current Protocol, Future Potential
Author: Millard DC, Clements M, Ross JD.
Product: Maestro Pro, Cardiac Module, Lumos MEA Plate, Lumos, Maestro Edge,
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Publication
A human brain microphysiological system derived from induced pluripotent stem cells to study neurological diseases and toxicity
Author: Pamies D, Barreras P, Block K, Makri G, Kumar A, Wiersma D, Smirnova L, Zhang C, Bressler J, Christian KM, Harris G, Ming GL, Berlinicke CJ, Kyro K, Song H, Pardo CA, Hartung T, Hogberg HT.
Product: Neural Module, Maestro Pro, Maestro Edge,
2016 SFN Poster Mak BrainPhys Neuronal Medium supports electrical activities of neurons derived from IPSC
Poster
BrainPhys neuronal medium supports the electrical activities of neurons derived from human pluripotent stem cells and primary CNS tissues in long-term cultures
Author: Mak CKH, Lee VM, Chew LH, McCormack K, Eaves AC, Thomas TE, Louis SA.
Product: Neural Module,
2016 SFN Poster Carlson iPSC-derived cortical neurons with epilepsy mutations
Poster
Leveraging iPSC-derived cortical neurons harboring known epilepsy mutations to advance personalized medicine
Author: Carlson C, McLachlan M, Dominguez E, Meline B, McMahon C, Strouse A, Burke T, DeLaura S, Jones E, Mangan K.
Product: Maestro Pro, Neural Module, Maestro Edge,
2016 SFN Poster Mangan Functional human neurons derived from iPS Cells
Poster
Functional human neurons derived from iPS cells display a range of unique and exciting MEA phenotypes
Author: Mangan K, Kannemeier C, Enghofer E, Ma J, DeLaura S, Carlson C.
Product: Maestro Pro, Neural Module, Maestro Edge,
2016 SFN Poster Kim Phenotyping of human iPSC-derived dopaminergic neurons
Poster
Phenotyping of human iPSC-derived dopaminergic neurons containing the engineered alpha-synuclein mutation
Author: Kim KH, Mangan K, Carlson C, Dickerson S, Burke T, Little L, Chase L, Swanson B, DeLaura S, Jones E.
Product: Maestro Pro, Neural Module, Maestro Edge,
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Publication
Identification of drug-drug interactions in vitro: a case study evaluating the effects of sofosbuvir and amiodarone on hiPSC-derived cardiomyocytes
Author: Millard DC, Strock CJ, Carlson CB, Aoyama N, Juhasz K, Goetze TA, Stoelzle-Feix S, Becker N, Fertig N, January CT, Anson BD, Ross JD.
Product: Maestro Pro, Cardiac Module, Maestro Edge,
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Publication
Evaluation of a Microelectrode Array-Based Assay for Neural Network Ontogeny Using Training Set Chemicals
Author: Brown JP, Hall D, Frank CL, Wallace K, Mundy WR, Shafer TJ.
Product: Maestro Pro, Neural Module, Maestro Edge,
2016 Nanion Poster Dekorte Pharmacological response to cardioactive compounds in hiPSC-CMs
Poster
Assessment of pharmacological responses to cardioactive compounds in human induced pluripotent stem cell-derived (hiPSC) cardiomyocytes using MEA and calcium transient analysis
Author: De Korte T, Stevenhagen F, Nacken P, Wilbers R, Langenberg K, Dunska M, Braam SR, Vlaming MLH
Product: Maestro Pro, Cardiac Module, Maestro Edge,
2016_stemcellreports_okubo_pretreatmentwithaysecretase.png
Publication
Pretreatment with a y-Secretase Inhibitor Prevents Tumor-like Overgrowth in Human iPSC-Derived Transplants for Spinal Cord Injury
Author: Okubo T, Iwanami A, Kohyama J, Itakura G, Kawabata S, Nishiyama Y, Sugai K, Ozaki M, Iida T, Matsubayashi K, Matsumoto M, Nakamura M, Okano H.
Product: Maestro Pro, Neural Module, CytoView MEA Plate, Maestro Edge,
2016_genomeres_mcsweeney_inhibitionofmicrorna128.png
Publication
Inhibition of microRNA 128 promotes excitability of cultured cortical neuronal networks
Author: McSweeney KM, Gussow AB, Bradrick SS, Dugger SA, Gelfman S, Wang Q, Petrovski S, Frankel WN, Boland MJ, Goldstein DB.
Product: Maestro Pro, Neural Module, CytoView MEA Plate, Maestro Edge,
2016_frontcellneurosci_galati_computersimulationssupporta.png
Publication
Computer simulations support a morphological contribution to BDNF enhancement of action potential generation
Author: Galati DF, Hiester BG, Jones KR.
Product: Neural Module,
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News
Human “Heartbeats-in-a-Dish” Takes Aim at Preventing Patient Deaths from Adverse Drug-Drug Interactions
Author: Axion BioSystems
Product: Maestro Pro, Cardiac Module, BioCircuit MEA Plate,
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Publication
Robust production of human neural cells by establishing neuroepithelial-like stem cells from peripheral blood mononuclear cell-derived feeder-free iPSCs under xeno-free conditions
Author: Isoda M, Kohyama J, Iwanami A, Sanosaka T, Sugai K, Yamaguchi R, Matsumoto T, Nakamura M, Okano H.
Product: Maestro Pro, Neural Module, CytoView MEA Plate, Maestro Edge,
2016_dismodelmech_preininger_ahumanpluripotentstem.png
Publication
A human pluripotent stem cell model of catecholaminergic polymorphic ventricular tachycardia recapitulates patient-specific drug responses
Author: Preininger MK, Jha R, Maxwell JT, Wu Q, Singh M, Wang B, Dalal A, Mceachin ZT, Rossoll W, Hales CM, Fischbach PS, Wagner MB, Xu C.
Product: Cardiac Module,
2016_jpharmacoltoxicolmethods_cavero_comprehensiveinvitroproarrhythmia.png
Publication
Comprehensive in vitro Proarrhythmia Assay (CiPA): Pending issues for successful validation and implementation
Author: Cavero I, Guillon JM, Ballet V, Clements M, Gerbeau JF, Holzgrefe H.
Product: Maestro Pro, Cardiac Module, Maestro Edge,
2016_nature_chailangkarn_ahumanneurodevelopmentalmodel.png
Publication
A human neurodevelopmental model for Williams syndrome
Author: Chailangkarn T, Trujillo CA, Freitas BC, Hrvoj-Mihic B, Herai RH, Yu DX, Brown TT, Marchetto MC, Bardy C, McHenry L, Stefanacci L, Järvinen A, Searcy YM, DeWitt M, Wong W, Lai P, Ard MC, Hanson KL, Romero S, Jacobs B, Dale AM, Dai L, Korenberg JR, Gage FH, Bellugi U, Halgren E, Semendeferi K, Muotri AR.
Product: Maestro Pro, Neural Module, CytoView MEA Plate, Maestro Edge,
2016_neurotoxicology_hondebrink_neurotoxicityscreeningofillicit
Publication
Neurotoxicity screening of (illicit) drugs using novel methods for analysis of microelectrode array (MEA) recordings
Author: Hondebrink L, Verboven AH, Drega WS, Schmeink S, de Groot MW, van Kleef RG, Wijnolts FM, de Groot A, Meulenbelt J, Westerink RH.
Product: Maestro Pro, Neural Module, Maestro Edge,
2016_jneurosci_yang_nav17a1632gmutation.png
Publication
Nav1.7-A1632G Mutation from a Family with Inherited Erythromelalgia: Enhanced Firing of Dorsal Root Ganglia Neurons Evoked by Thermal Stimuli
Author: Yang Y, Huang J, Mis MA, Estacion M, Macala L, Shah P, Schulman BR, Horton DB, Dib-Hajj SD, Waxman SG.
Product: Maestro Pro, Neural Module, CytoView MEA Plate, Maestro Edge,