Marchiano S, Hsiang TY, Higashi T, Akshita Khanna A, Hans Reinecke H, Xiulan Yang X, Pabon L, Sniadecki NJ, Bertero A, Gale Jr M, Murry CE
Stem Cell Reports, 2021
Summary:
This study demonstrated that SARS-CoV-2 readily infects and replicates within human pluripotent stem cell cardiomyoctyes (hPSC-CMs), resulting in rapid cell death. Furthermore, infected hPSC-CMs show a progressive impairment in both electrophysiological and contractile properties.
