Zili Gao, Jia Guo, Bo Gou, Zhen Gu, Tan Jia, Sinan Ma, Liyuan Jiang, Wenli Liu, Lixun Zhou, and Qi Gu
Bioactive Materials, 24 May 2023
The role of trophoblast mechanics during embryo implantation is not fully understood. In this study, scientists construct an innovative in vitro model to explore the effect of stiffness changes in mouse trophoblasts stem cells upon implantation, using the Lux live-cell imaging platform to monitor the difference in adhesion rate, expansion area and invasion depth of the mouse trophoblast stem cells, compared to different Young's moduli.
