Integration of toxicodynamic and toxicokinetic new approach methods into a weight-of-evidence analysis for pesticide developmental neurotoxicity assessment: A case-study with DL- and L-glufosinate

Authors: Dobreniecki S, Mendez E, Lowit A, Freudenrich TM, Wallace K, Carpenter A, Wetmore BA, Kreutz A, Korol-Bexell E, Friedman KP, and Shafer TJ.

Regulatory Toxicology and Pharmacology, 2022.

 

Scientists use Axion’s MEA platform to assess the effects of  DL-glufosinate ammonium isomers on network formation in vitro and inform the need for an in vivo DNT study.