Flotillins in the intercalated disc are potential modulators of cardiac excitability

Kessler EL, van Stuijvenberg L, van Bavel JJA, van Bennekom J, Zwartsen A, Rivaud MR, Vink A, Efimov IR, Postma AV, Peter van Tintelen J, Remme CA, Vos MA, Banning A, de Boer TP, Tikkanen R, van Veen TAB.

J Mol Cell Cardiol, 2018

Summary:

See how Maestro technology helped researchers demonstrate the presence of Flotillin-1 and Flotillin-2 in the cardiac ID, indicating a role of Flotillins on Nav1.5 expression at the ID with potential consequences for cardiac excitation.