Wei F, Pourrier M, Strauss DG, Stockbridge N, Pang L.
Tox Sci, 2020
Summary:
Researchers compared hiPSC-CMs in a Maestro MEA to evaluate the response to classic cardiac ion channel blockers under spontaneous and stimulated (both electrical and optogenetic pacing) beating conditions.
Keywords: CiPA, human induced pluripotent stem cell-derived cardiomyocytes, cardiac safety, proarrhythmia, beat rates, electrical pacing, optogenetic pacing, adult cardiomyocytes, drug effects
