Derivation of human midbrain-specific organoids from neuroepithelial stem cells

Monzel AS, Smits LM, Hemmer K, Hachi S, Moreno EL, van Wuellen T,  Jarazo J, Walter J, Brüggemann I, Boussaad I, Berger E, Fleming RMT, Bolognin S, Schwamborn JC.

Stem Cell Reports, 2017


See how Maestro MEA technology makes it possible to use a midbrain organoid system for advanced in vitro disease modeling and therapy development.

Keywords: Parkinson's disease, midbrain, organoid, spheroid, mini-brain, dopaminergic, myelination, synapse

Derivation of Human Midbrain-Specific Organoids from Neuroepithelial Stem Cells