Hit-to-lead optimization

You need the right assay to make the right decisions.

An assay that is sensitive, accurate, and captures the data you need in vitro to predict outcomes in the clinic. For oncological therapeutic development, an assay to optimize tumor killing potency while minimizing off-tumor liabilities.​

Optimize your candidate potency and accelerate development with the Maestro Z platform.

Transform your drug development

The Maestro Z platform is the premier impedance-based assay platform for high quality, real-time cell health & cytotoxicity data. Ideal for assessing candidate potency, the system features:​

 

Full response profiling – Real-time, kinetic cell killing data captures the full cytotoxic response on one plate with no additional workload. ​
 

Sensitive & reproducible data – Cellular impedance is a proven technique to monitor subtle changes to cell health. A tightly controlled environment and no reagents or complicated steps, minimizes variables that can confound results. ​​
 

Scalable throughput – With an array of systems and throughputs available you can expand your capabilities as your needs grow.​ ​
 

A kinetic assay easier than endpoint assays​

Just plate your cells to start the assay and see every moment from start to finish.

Observe dynamic cell killing and avoid the variability of single endpoint measurements for better decision making. ​

Don’t miss time-dependent responses to help predict optimal dosing regimens.​ ​

Capture and analyze every moment for fast, actionable results.​

See how easy it is to add high quality, kinetic data to accelerate your pipeline. The Maestro Z platform is optimized to make the whole process as convenient as possible:

• >> Automated event tracking and acquisition
• >> Fast, intuitive data analysis​
• >> Integrated temperature and CO₂ ​(Benchtop models)
• >> Built-in barcode plate/data tracking​​
• >> API for 3^rd party automation integration​
• >> 21 CFR Part 11 compliance ​​(optional)