Functional Characterization of Cell-Based Therapeutics

The functional characterization of complex interactions between cancer cells and effector cells in vitro enables deep insights into the anti-tumor activity of immunotherapy candidates. Discover how functional assays on Axion’s label-free live-cell analysis platforms can transform your preclinical research and development. 

>> Benefits of real-time assays

>> Immuno-oncology applications

>> Publications

Maestro Z Impedance In Vitro Potency Assay Data

 

 

Benefits of Real-Time Functional Analysis

 

Axion’s Maestro Z live-cell analysis platforms use impedance biosensors technology to capture your entire experiment – allowing you to analyze the magnitude and kinetics of cell-mediated killing and its persistence over time. 

  • >> Easy – minimal hands-on time; just put your cells on the system and walk away
  • >> Sensitive – detect small variations between donors and E:T ratios
  • >> Label-free – no optimization of labels or dyes
  • >> Reproducible – biology is variable enough without having to worry about your assay system
  • >> Scalable – with single plate to modular multi-plate options, there’s a system to suit your needs

 

Full Pipeline Support

 

 

 

Immuno-Oncology Applications

Flexible, easy, and sensitive, our systems capture real-time anti-tumor interactions for a wide range of applications:

 

ADCC

 

ADCC

 

Solid Tumors

 

Solid Tumors

 

NK Cells

 

NK Cells

 

BiTEs

 

BiTEs

 

 

 

See how researchers are using our technology to support their therapeutic discoveries >> 

 

 

 

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