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Modeling epilepsy-related SCN2A mutation L1342P with CRISPR/Cas9-edited human-induced pluripotent stem cell-derived cortical spheroids
Poster
Modeling epilepsy-related SCN2A mutation L1342P with CRISPR/Cas9-edited human-induced pluripotent stem cell-derived cortical spheroids
Author: Maria I. Olivero-Acosta, Zhefu Que, Conrad Otterbacher, Muhan Wang, Trang Nguyen, Ningren Cui, Xiaoling Chen, Jingliang Zhang, Kyle Wettschurack, Jiaxiang Wu, William C, Skarnes, Yang Yang
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
Properties of Human Stem Cell-derived Neurons in Long-term Cell Culture as a Model for Antiseizure Drug Discovery
Poster
Properties of Human Stem Cell-derived Neurons in Long-term Cell Culture as a Model for Antiseizure Drug Discovery
Author: Hamed Salmanzadeh and Robert F. Halliwell
Product: Maestro Edge, CytoView MEA Plate, Neural Module,
Diminished motor neuron activity driven by abnormal astrocytic GLAST glutamate transporter in spinal muscular atrophy is not fully restored after lentiviral SMN delivery
Poster
Diminished motor neuron activity driven by abnormal astrocytic GLAST glutamate transporter in spinal muscular atrophy is not fully restored after lentiviral SMN delivery
Author: Emily Welby, Ph.D.
Product: CytoView MEA Plate, Neural Module,
Evaluating the Influence of HCMV Infection on Alzheimer’s Disease Pathology
Poster
Evaluating the Influence of HCMV Infection on Alzheimer’s Disease Pathology
Author: Jacob W. Adelman, Megan L. Schumacher, Benjamin S. O’Brien, Suzette Rosas-Rogers, Scott S. Terhune, Allison D. Ebert
Product: CytoView MEA Plate, Neural Module,
Liquid tumor app note
Application Note
Development of an in vitro cell killing assay for liquid tumor cancer cells
Author: Axion BioSystems
Product: Maestro Z, Impedance Module, CytoView-Z Plate,
Biological Psychiatry Publication 13 March 2023
Publication
Loss of CNTNAP2 alters human cortical excitatory neuron differentiation and neural network development
Author: F. George-Hyslop, M. Haneklaus, T. Kivisild, F. Livesey
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
OmniFL-publication_Neuro
Publication
Elevated ROS levels during the early development of Angelman syndrome alter the apoptotic capacity of the developing neural precursor cells
Author: Lilach Simchi, Pooja Kri Gupta, Yonatan Feuermann, and Hanoch Kaphzan
Product: Omni,
2023 Renal Physiology Functional TFEB activation characterizes multiple models of renal cystic disease
Publication
Functional TFEB activation characterizes multiple models of renal cystic disease and loss of polycystin-1
Author: Shillingford JM and Shayman JA
Product: Exact FL, Cell Counting Module, Corning Cell Counter,
Electrically-evoked oscillating calcium transients in mono- and co-cultures of iPSC glia and sensory neurons
Publication
Electrically-evoked oscillating calcium transients in mono- and co-cultures of iPSC glia and sensory neurons
Author: Jennifer Lawson, Eli LaVancher, Mauricio De Almeida, and Bryan J. Black
Product: Neural Module, Maestro Pro, CytoView MEA Plate,
Nav1.7 P610T mutation
Publication
Nav1.7 P610T mutation in two siblings with persistent ocular pain after corneal axon transection: impaired slow inactivation and hyperexcitable trigeminal neurons
Author: Mohammad-Reza Ghovanloo, Philip R. Effraim, Jun-Hui Yuan, Betsy R. Schulman, Deborah S. Jacobs, Sulayman D. Dib-Hajj, and Stephen G. Waxman
Product:
Neuronal extracellular vesicles
Publication
Neuronal extracellular vesicles and associated microRNAs induce circuit connectivity downstream BDNF
Author: Anna Antoniou, Loic Auderset, Lalit Kaurani, Eva Sebastian, Yuzhou Zeng, Maria Allahham,
Silvia Cases-Cunillera, Susanne Schoch, Jan Grundemann, Andre Fischer, and Anja Schneider
Product:
Microfabricated polymer-metal biosensors
Publication
Microfabricated polymer-metal biosensors for multifarious data collection from electrogenic cellular models
Author: Charles M. Didier, Julia F. Orrico, Omar S. Cepeda Torres, Jorge Manrique Castro, Aliyah Baksh, and
Swaminathan Rajaraman
Product:
Introducing Omni Pro 12
Video
Introducing Omni Pro 12
Axion BioSystems
Product: Omni Pro 12, Omni, Organoid Analysis Module, Scratch Assay Module, Clonogenic Assay Module, Confluency Module,
An Optimized Workflow to Generate and Characterize iPSC-Derived Motor Neuron (MN) Spheroids
Publication
An Optimized Workflow to Generate and Characterize iPSC-Derived Motor Neuron (MN) Spheroids
Author: María José Castellanos-Montiel , Mathilde Chaineau , Anna Kristyna Franco-Flores, Ghazal Haghi,
Dulce Carrillo-Valenzuela, Wolfgang E. Reintsch , Carol X.-Q. Chen and Thomas M. Durcan
Product:
Kv7-specific activators
Publication
Kv7-specific activators hyperpolarize resting membrane potential and modulate human iPSC-derived sensory neuron excitability
Author: Mark Estacion, Shujun Liu, Xiaoyang Cheng, Sulayman Dib-Hajj, and Stephen G. Waxman
Product:
Injectable Contraceptive
Publication
Injectable Contraceptive, Depo-Provera, Produces Erratic Beating Patterns in Patient-Specific Induced Pluripotent Stem Cell-derived Cardiomyocytes with Type 2 Long QT Syndrome
Author: Pinsky AM, Gao X, Bains S, Kim CSJ, Louradour J, Odening KE, Tester DJ, Giudicessi JR, Ackerman MJ
Product: Maestro Edge, Cardiac Module, BioCircuit MEA Plate,
Biosensing system for drug evaluation of amyotrophic lateral sclerosis
Publication
Biosensing system for drug evaluation of amyotrophic lateral sclerosis based on muscle bundle and nano-biohybrid hydrogel composed of multiple motor neuron spheroids and carbon nanotubes
Author: T. Ha, S. Park, M. Shin, J-Y. Lee, J-H. Choi, J-W. Choi
Product: Maestro Edge, Neural Module, CytoView MEA Plate,
preview image
Publication
Natural variation in gene expression and viral susceptibility revealed by neural progenitor cell villages
Author: MF Wells, J Nemesh, S Ghosh, JM Mitchell, MR Salick, CJ Mello, D Meyer, O Pietilainen, F Piccioni, EJ Guss, K Raghunathan, M Tegtmeyer, D Hawes, A Neumann, KA Worringer, S Kommineni, K Chan, BK Peterson, JJ Raymond, SA McCarroll
Product: Neural Module, CytoView MEA Plate,
Sophoridine manifests as a leading compound for anti-arrhythmia with multiple ion-channel blocking effects
Publication
Sophoridine manifests as a leading compound for anti-arrhythmia with multiple ion-channel blocking effects
Author: T Song, Y Hao, M Wang, T Li, C Zhao, J Li, Y Hou
Product: Maestro Edge, Cardiac Module, BioCircuit MEA Plate,
preview image
Publication
Selective inhibition of excitatory synaptic transmission alters the emergent bursting dynamics of in vitro neural networks
Author: JS Weir, N Christiansen, A Sandvig, I Sandvig
Product: Maestro Pro,