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FTH promotes the proliferation and renders the HCC cells specifically resist to ferroptosis by maintaining iron homeostasis
Author: Hu W, Zhou C, Jing Q, Li Y, Yang J, Yang C, Wang L, Hu J, Li H, Wang H, Yuan C, Zhou Y, Ren X, Tong X, Du J, and Wang Y.
Product: Maestro Z, Impedance Module, CytoView-Z Plate,
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Publication
Using hiPSC-CMs to Examine Mechanisms of Catecholaminergic Polymorphic Ventricular Tachycardia
Author: Arslanova A, Shafaattalab S, Ye K, Asghari P, Lin L, Kim B, Roston TM, Hove-Madsen L, Van Petegem F, Sanatani S, Moore E, Lynn F, Søndergaard M, Luo Y, Chen SRW, and Tibbits GF.
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Junctional instability in neuroepithelium and network hyperexcitability in a focal cortical dysplasia human model
Author: Avansini SH, Puppo F, Adams JW, Vieira AS, Coan AC, Rogerio F, Torres FR, Araújo PAOR, Martin M, Montenegro MA, Yasuda CL, Tedeschi H, Ghizoni E, França AFEC, Alvim MKM, Athié MC, Rocha CS, Almeida VS, Dias EV, Delay L, Molina E, Yaksh TL, Cendes F, Lopes Cendes I, and Muotri AR.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
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Publication
HDAC6 Inhibition Corrects Electrophysiological and Axonal Transport Deficits in a Human Stem Cell-Based Model of Charcot-Marie-Tooth Disease (Type 2D)
Author: Smith AST, Kim JH, Chun C, Gharai A, Moon HW, Kim EY, Nam SH, Ha N, Song JY, Chung KW, Doo HM, Hesson J, Mathieu J, Bothwell M, Choi BO, and Kim DH.
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E3 ubiquitin ligase Nedd4-2 exerts neuroprotective effects during endoplasmic reticulum stress
Author: Lodes DE, Zhu J, and Tsai N-P.
Product: Neural Module,
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Publication
Integrated Omic Analyses Identify Pathways and Transcriptomic Regulators Associated with Chemical Alterations of in Vitro Neural Network Formation
Author: Marable CA, Frank CL, Seim RF, Hester S, Henderson WM, Chorley B, and Shafer TJ.
Product: Maestro Edge, Neural Module, CytoView MEA Plate,
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Publication
Human Spinal Organoid-on-a-Chip to Model Nociceptive Circuitry for Pain Therapeutics Discovery
Author: Ao Z, Cai H, Wu Z, Krzesniak J, Tian C, Lai YY, Mackie K, and Guo F.
Product: Maestro Edge, Neural Module, CytoView MEA Plate,
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Publication
Assessment of cerebral spinal fluid biomarkers and microRNA-mediated disease mechanisms in spinal muscular atrophy patient samples
Author: Welby E, Rehborg RJ, Harmelink M, and Ebert AD.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
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Shed CNTNAP2 ectodomain is detectable in CSF and regulates Ca2+ homeostasis and network synchrony via PMCA2/ATP2B2
Author: Martín-de-Saavedra MD, Dos Santos M, Culotta L, Varea O, Spielman BP, Parnell E, Forrest MP, Gao R, Yoon S, McCoig E, Jalloul HA, Myczek K, Khalatyan N, Hall EA, Turk LS, Sanz-Clemente A, Comoletti D, Lichtenthaler SF, Burgdorf JS, Barbolina MV, Savas JN, Penzes P.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
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Publication
Phenotypic Variability in iPSC-Induced Cardiomyocytes and Cardiac Fibroblasts Carrying Diverse LMNA Mutations
Author: Yang J, Argenziano MA, Burgos Angulo M, Bertalovitz A, Beidokhti MN, and McDonald TV.
Product: Maestro Edge, Cardiac Module, CytoView MEA Plate,
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Publication
The Linkage Phase of the Polymorphism KCNH2-K897T Influences the Electrophysiological Phenotype in hiPSC Models of LQT2
Author: van den Brink L, Brandão KO, Yiangou L, Blanch-Asensio A, Mol MPH, Mummery CL, Verkerk AO, and Davis RP.
Product:
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Bacterial neurotoxic metabolites in multiple sclerosis cerebrospinal fluid and plasma
Author: Ntranos A, Park HJ, Wentling M, Tolstikov V, Amatruda M, Inbar B, Kim-Schulze S, Frazier C, Button J, Kiebish MA, Lublin F, Edwards K, and Casaccia P.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
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Publication
(preprint) STRAIGHT-IN: A platform for high-throughput targeting of large DNA payloads into human pluripotent stem cells
Author: Grandela C, Blanch-Asensio A, Brandão KO, de Korte T, Yiangou L, Mol MPH, van Meer BJ, Mummery CL, and Davis RP.
Product:
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News
COVID-19 Therapeutic Discovery Using a Bioelectronic Assay
Author: James Ross, PhD
Product: Maestro Z, Impedance Module, CytoView-Z Plate,
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Publication
16pdel lipid changes in iPSC-derived neurons and function of FAM57B in lipid metabolism and synaptogenesis
Author: Tomasello DL, Kim JL, Khodour Y, McCammon JM, Mitalipova M, Jaenisch R, Futerman AH, and Sive H.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
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Activation of retinal ganglion cells using a biomimetic artificial retina
Author: Greco JA, Wagner NL, Jensen RJ, Lawrence DB, Ranaghan MJ, Sandberg MN, Sandberg DJ, and Birge RR.
Product: Neural Module,
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Pathophysiological metabolic changes associated with disease modify the proarrhythmic risk profile of drugs with potential to prolong repolarisation
Author: TeBay C, McArthur JR, Mangala M, Kerr N, Heitmann S, Perry MD, Windley MJ, Vandenberg JI, and Hill AP.
Product: Maestro Pro, Cardiac Module, CytoView MEA Plate,
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Publication
Marine and Anthropogenic Bromopyrroles Alter Cellular Ca 2+ Dynamics of Murine Cortical Neuronal Networks by Targeting the Ryanodine Receptor and Sarco/Endoplasmic Reticulum Ca 2+-ATPase
Author: Zheng J, Antrobus S, Feng W, Purdy TN, Moore BS, and Pessah IN.
Product:
MEA viability application note
Application Note
Validation of a structure-function assay for neurotoxicity in primary and hiPSC-derived neurons
Author: Axion BioSystems
Product: MEA Viability Module, Maestro Pro,
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Publication
Mutations of the histone linker H1–4 in neurodevelopmental disorders and functional characterization of neurons expressing C-terminus frameshift mutant H1.4
Author: Tremblay MW, Green MV, Goldstein BM, Aldridge AI, Rosenfeld JA, Streff H, Tan WD, Craigen W, Bekheirnia N, Al Tala S, West AE, and Jiang YH.
Product: Maestro Edge, Neural Module, CytoView MEA Plate,