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Autism-linked Cullin3 germline haploinsufficiency impacts cytoskeletal dynamics and cortical neurogenesis through RhoA signaling
Author: M. Amar, A. B. Pramod, N. K. Yu, V. M. Herrera, L. R. Qiu, P. Moran-Losada, P. Zhang, C. A. Trujillo, J. Ellegood, J. Urresti, K. Chau, J. Diedrich, J. Chen, J. Gutierrez, J. Sebat, D. Ramanathan, J. P. Lerch, J. R. Yates III, A. R. Muotri, and L. M. Iakoucheva
Product: Maestro Edge, Neural Module, CytoView MEA Plate,
What is MEA (microelectrode array) video
Video
What is MEA (microelectrode array) technology?
Axion BioSystems
Product: Maestro Pro, Maestro Edge, Neural Module, Cardiac Module, BioCircuit MEA Plate, CytoView MEA Plate,
human stem-cell derived test system for neuronal signaling on multiwell MEA system
Publication
A human stem cell‑derived test system for agents modifying neuronal N‑methyl‑d‑aspartate‑type glutamate receptor Ca2+‑signalling
Author: Klima S, Brüll M, Spreng A-S, Suciu I, Falt T, Schwamborn JC, Waldmann T, Karreman C, Leist M.
Product: Maestro Edge, Neural Module, CytoView MEA Plate,
isogenic sets
Publication
Isogenic sets of hiPSC-CMs harboring distinct KCNH2 mutations differ functionally and in susceptibility to drug-induced arrhythmias
Author: Brandao K, van den Brink L, Miller DC, Grandela C, van Meer BJ, Mol MPH, de Korte T, Tertoolen LGJ, Mummery CL, Sala L, Verkerk AO, and P. Davis R
Product: Maestro Pro, Cardiac Module, Maestro Edge,
sfN 2021 Poster on brain turmors and epilepsy mechanism recorded on multiwell MEA system
Poster
IDH mutated tumors promote epileptogenesis via D-2-HG dependent mTOR hyperactivation
Author: Mortazavi A, Fayed I, Bachani M, Ksendzovsky A, Maric D, Dowdy T, Larion M, Yang CZ, Zaghloul KA.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
Acute Brain Slice Protocol on MEA platform
Culture Protocol
Acute Brain Slice Protocol
Author: Axion BioSystems
Product: Maestro Pro, Neural Module, CytoView MEA Plate, Maestro Edge,
2021 Rybak wolf brain organoids with herpes
Publication
Neurodegeneration in human brain organoids infected with herpes simplex virus type 1
Author: Rybak-Wolf A, Wyler E, Legnini I, Loewa A, Glažar P, Kim SJ, Pentimalli TM, Martinez AO, Beyersdorf B, Woehler A, Landthaler M and Rajewsky N.
Product: Maestro Pro, Neural Module, BioCircuit MEA Plate,
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Publication
The enhancement of activity rescues the establishment of Mecp2 null neuronal phenotypes
Author: Scaramuzza L, De Rocco G, Desiato G, Cobolli Gigli C, Chiacchiaretta M, Mirabella F, Pozzi D, De Simone M, Conforti P, Pagani M, Benfenati F, Cesca F, Bedogni F, and Landsberger N.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
Brain tumors that cause epilepsy study in vitro
Coffee Break Webinar
Brain tumors that cause epilepsy
Author: Armin Mortazavi
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
2021 Covid-19 treatment and hiPSC-CMs proarrythmia
Publication
[PRE-PRINT] Comprehensive preclinical evaluation of how cardiac safety profiles of potential COVID-19 drugs are modified by disease associated factors
Author: TeBay C, McArthur J, Mangala M, Kerr N, Heitmann S, Matthew Perry M, Windley M, VaAndenberg J, Hill A.
Product: Cardiac Module, BioCircuit MEA Plate,
2021 Tomasello zebrafish electrophysiology
Publication
[PRE-PRINT] FAM57B is a modulator of ceramide synthesis that regulates sphingolipid homeostasis and synaptic composition in the developing brain
Author: Tomasello DL, Kim JL, Khodour Y, McCammon JM, Mitalipova M, Jaenisch R, Futerman AH and Sive H.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
Brain slice on microelectrode array
Publication
[PRE-PRINT] Heterogeneity and excitability of BRAFV600E-induced tumors is determined by PI3K/mTOR-signaling state and Trp53-loss
Author: Cases-Cunillera S, van Loo KMJ, Pitsch J, Quatraccioni A, Sivalingam S, Salomoni P, Dietrich D, Schoch S, Becker AJ.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
Engineering hiPSC-CM and hiPSC-EC laden 3D nanofibrous splenic hydrogel for improving cardiac function through revascularization and remuscularization in infarcted heart
Publication
Engineering hiPSC-CM and hiPSC-EC laden 3D nanofibrous splenic hydrogel for improving cardiac function through revascularization and remuscularization in infarcted heart
Author: Guan G, Huo D, Li Y, Zhao X, Li Y, Qin Z, Sun D, Yang G, Yang M, Tan J, Zeng W, and Zhu C.
Product: Maestro Pro, Cardiac Module, CytoView MEA Plate,
What is TEER or Barrier Assay
Video
What is TEER?
Axion BioSystems
Product: Maestro Z, Maestro ZHT, CytoView-Z Plate, Impedance Module, GxP Impedance Module, Impedance Automation Module,
(2021) Conserved residues in the extracellular loop 2 regulate Stachel-mediated activation of ADGRG2
Publication
Conserved residues in the extracellular loop 2 regulate Stachel-mediated activation of ADGRG2
Author: Gad AA, Azimzadeh P, Balenga N.
Product: Maestro Z, Impedance Module, CytoView-Z Plate, Maestro ZHT,
2020 SARS-CoV-2 and cardiomyoctyes
Publication
SARS-CoV-2 infects human pluripotent stem cell-derived cardiomyocytes, impairing electrical and mechanical function
Author: Marchiano S, Hsiang TY, Higashi T, Akshita Khanna A, Hans Reinecke H, Xiulan Yang X, Pabon L, Sniadecki NJ, Bertero A, Gale Jr M, Murry CE
Product: Maestro Z, Impedance Module, CytoView-Z Plate, Maestro Pro, Maestro Edge,
2021 publication on neanderthal cortical organoids
Publication
Reintroduction of the archaic variant of NOVA1 in cortical organoids alters neurodevelopment
Author: Trujillo CA, Rice ES, Schaefer NK, Chaim IA, Wheeler EC, Madrigal AA, Buchanan J, Preissl S, Wang A, Negraes PD, Szeto RA, Herai RH, Huseynov A, Ferraz MSA, Borges FS, Kihara AH, Byrne A, Marin M, Vollmers C, Brooks AN, Lautz JD, Semendeferi K, Shapiro B, Yeo GW, Smith SEP, Green RE, Muotri AR.
Product: Maestro Pro, Neural Module, CytoView MEA Plate,
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Publication
Generation of region-specific and high-purity neurons from human feeder-free iPSCs
Author: Sato T, Imaizumi K, Watanabe H, Ishikawa M, Okano H
Product: Maestro Pro, Neural Module,
Cell Plating Calculator
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Cell Plating Calculator "How To" Guide
Author: Axion BioSystems
Product: BioCircuit MEA Plate, CytoView MEA Plate, CytoView-Z Plate, Lumos MEA Plate, Lumos OptiClear Plate,
Axion Bio Cell Plating Calculator Quick Guide
Product Brochure
Cell Plating Calculator Guide
Author: Axion BioSystems
Product: CytoView MEA Plate, CytoView-Z Plate, BioCircuit MEA Plate, Lumos MEA Plate, Lumos OptiClear Plate,