Synaptic and intrinsic membrane defects disrupt early neural network dynamics in Down syndrome

Authors: Saad B. Hannan, Ivan Alić, Aoife Murray, Joonhong Kwon, Martin Mortensen, Hyo Jung Kang, Ante Plećaš, Pollyanna A. Goh, Niamh L. O’Brien, Richard Naud, Dean Nižetić, and Trevor G. Smart

Nature Communications, 22 January 2026