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  4. Effects of dibenzazepine compounds on Nav1.2 channels and neuronal network activity: A systematic comparison

Effects of dibenzazepine compounds on Nav1.2 channels and neuronal network activity: A systematic comparison

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Authors: Kunihiko Araki, Merlin Felix Schwering-Sohnrey, Griselda Marku, Michael Wenzel, Susanne Schoch, Thoralf Opitz, and Heinz Beck

European Journal of Pharmacology, 12 September 2025

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Microglial regulation of hyperexcitability in cortical neurons derived from human iPSCs carrying epilepsy-associated sodium channel Nav1.2 variant

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At Axion BioSystems, our goal is to help you capture the complex biology of your cells. Whether monitoring the kinetics of cellular growth and death or recording the activity of excitable cells; Axion BioSystems' live-cell assay technology can help you record it noninvasively, in real time, and with software tools to make analysis quick and painless.

 

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  • Products
    • MEA
      • Maestro Pro
      • Maestro Edge
      • Maestro Volt
      • MEA Software
        • Neural Module
        • MEA Viability Module
        • Cardiac Module
        • MEA Automation Module
        • GxP Impedance Module
        • Impedance Automation Module
        • Impedance Module
      • Lumos
      • MEA Creator Kit
      • MEA Plates
        • Organoid MEA
        • BioCircuit MEA Plate
        • CytoView MEA Plate
        • Lumos MEA Plate
        • SpheroGuide MEA Plate
      • Connected Lab
    • Cell Analysis
      • Maestro Z
      • Maestro ZHT
      • Maestro TrayZ
      • Cell Analysis Software
        • Impedance Module
        • GxP Impedance Module
        • Impedance Automation Module
      • CytoView-Z Plate
    • Imaging
      • Omni Pro 12
      • Omni
      • Lux
      • Imaging Software
        • Clonogenic Assay Module
        • Confluency Module
        • Fluorescence Module
        • iPSC Module
        • Organoid Analysis Module
        • Scratch Assay Module
      • Connected Lab
    • Cell Counting
      • Corning Cell Counter
      • Exact FL
      • Cell Counting Software
        • Cell Counting Module
        • Organoid Counting Module
  • Applications
    • Cardiac Activity
      • Cardiac Characterization
      • Cardiac Classification
      • Cardiac Development
      • Cardiomyocyte Pacing
      • Cardiotoxicity and Safety
      • Inotropy
    • Cell-based Assays
      • Barrier Function
      • Cell Counting
      • Cell Migration and Scratch Assays
      • Cell Proliferation
      • Cell Signaling
      • Clonogenic Assay
      • Cytotoxicity and Cell Viability
      • Transfection and Transduction
      • Organ-on-a-chip
    • Neural Activity
      • Neural Characterization and Development
      • Neural Circuit and Innervation
      • Neural Co-culture and Glial Interaction
      • Neural Optical and Electrical Stimulation
      • Neural Organoids
      • Neurological Disease
        • Alzheimer's Disease
        • Amyotrophic Lateral Sclerosis (ALS)
        • Autism
        • Epilepsy
        • Glioma
        • Parkinson's Disease
      • Neuromuscular Junction
      • Neurotoxicology and Safety
      • Pain
      • Retina
      • Zebrafish
    • Oncology
      • Cancer Spheroid
      • Cell Proliferation
      • Clonogenic Assay
      • Cytotoxicity and Cell Viability
      • Glioma
      • Immuno-oncology Assays
        • Antibody-dependent cellular cytotoxicity (ADCC)
        • CAR T Cell Killing
        • Cell Migration and Scratch Assays
        • NK Cell Killing
      • Liquid Tumors
    • Stem Cell Culture
      • Cardiac Development
      • iPSC Organoid Models​
      • Neural Characterization and Development
      • Neural Organoids
      • Organ-on-a-chip
      • Stem Cell Monitoring
    • Virology
      • Antiviral Drug Studies
      • Viral Titer
  • Resources
    • Axion iPSC Model Standards (AIMS)
    • Cell Plating Calculator
    • Resources
    • Resources for Publishing Your Research
    • Research Grant Resources
    • Customer Stories
  • About Us
    • Locations
    • Join Our Team
    • Leadership Team
    • Neuroscience Scientific Advisory Board
    • Our History
    • Technology
    • Travel Awards
    • Events
    • Axion World Tour
    • Contract Research Organizations
    • Scientific Web Tools
  • Contact Us
  • Search