Resources
Axion Bio App Note Maturity
Application Note
Fast functional maturity
Author: Axion BioSystems
Product: Maestro Pro, 心筋モジュール, CytoView MEA プレート, Maestro Edge,
2018_brjpharmacol_yang_reversepharmacogenomicscarbamazepinenormalizes.png
Publication
Reverse pharmacogenomics: carbamazepine normalizes activation and attenuates thermal hyperexcitability of sensory neurons due to Nav1.7 mutation I234T
Author: Yang Y, Adi T, Effraim PR, Chen L, Dib-Hajj SD, Waxman SG.
Product: Maestro Pro, 神経モジュール, CytoView MEA プレート, Maestro Edge,
2018_scirep_derosa_convergentpathwaysinidiopathic.png
Publication
Convergent pathways in idiopathic autism revealed by time course transcriptomic analysis of patient-derived neurons
Author: DeRosa BA, El Hokayem J, Artimovich E, Garcia-Serje C, Phillips AW, Van Booven D, Nestor JE, Wang L, Cuccaro ML, Vance JM, Pericak-Vance MA, Cukier HN, Nestor MW, Dykxhoorn DM.
Product: 神経モジュール, Maestro Pro, Maestro Edge, CytoView MEA プレート,
2018_elife_chia_ahomozygouslossof.png
Publication
A homozygous loss-of-function CAMK2A mutation causes growth delay, frequent seizures and severe intellectual disability
Author: Chia PH, Zhong FL, Niwa S, Bonnard C, Utami KH, Zeng R, Lee H, Eskin A, Nelson SF, Xie WH, Al-Tawalbeh S, El-Khateeb M, Shboul M, Pouladi MA, Al-Raqad M, Reversade B.
Product: 神経モジュール, Maestro Pro, Maestro Edge,
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Poster
CiPA Phase II: Validation Study Results
Author: Blinova K.
Product: Maestro Pro, Maestro Edge, 心筋モジュール,
2018_plosone_moyer_pharmacologicalcharacterizationofpotent.png
Publication
Pharmacological characterization of potent and selective NaV1.7 inhibitors engineered from Chilobrachys jingzhao tarantula venom peptide JzTx-V
Author: Moyer BD, Murray JK, Ligutti J, Andrews K, Favreau P, Jordan JB, Lee JH, Liu D, Long J, Sham K, Shi L, Stöcklin R, Wu B, Yin R, Yu V, Zou A, Biswas K, Miranda LP.
Product: 神経モジュール, Maestro Pro, Maestro Edge,
(2018) Witkin et al. Bioisosteres of Ethyl 8-Ethynyl-6-(Pyridin-2-yl)-4H- benzo[f]imidazo [1, 5-a][1,4]diazepine-3-carboxylate (HZ-166) as Novel Alpha 2,3 Selective Potentiators of GABAA Receptors: Improved Bioavailability Enhances Anticonvulsant Efficacy
Publication
Bioisosteres of ethyl 8-ethynyl-6-(pyridin-2-yl)-4H-benzo[f]imidazo [1,5-a][1,4]diazepine-3-carboxylate (HZ-166) as novel alpha 2,3 selective potentiators of GABAA receptors: improved bioavailability enhances anticonvulsant efficacy
Author: Witkin JM, Smith JL, Ping X, Gleason SD, Poe MM, Li G, Jin X, Hobbs J, Schkeryantz JM, McDermott JS, Alatorre AI, Siemian JN, Cramer JW, Airey DC, Methuku KR, Tiruveedhula VVNPB, Jones TM, Crawford J, Krambis MJ, Fisher JL, Cook JM, Cerne R.
Product: 神経モジュール, Maestro Pro, Maestro Edge,
(2018) Sarkar et al. Efficient Generation of CA3 Neurons from Human Pluripotent Stem Cells Enables Modeling of Hippocampal Connectivity In Vitro
Publication
Efficient generation of CA3 neurons from human pluripotent stem cells enables modeling of hippocampal connectivity in vitro
Author: Sarkar A, Mei A, Paquola ACM, Stern S, Bardy C, Klug JR, Kim S, Neshat N, Kim HJ, Ku M, Shokhirev MN, Adamowicz DH, Marchetto MC, Jappelli R, Erwin JA, Padmanabhan K, Shtrahman M, Jin X, Gage FH.
Product: 神経モジュール, Maestro Pro, Maestro Edge,
Axion Bio - Culture Protocol - CDI Cardiomyocytes2
Culture Protocol
CDI iCell Cardiomyocytes^2 Application Protocol
Author: Axion BioSystems
Product: Maestro Pro, 心筋モジュール, CytoView MEA プレート, Maestro Edge,
2018_toxicolsci_millard_crosssitereliabilityof.png
Publication
Cross-site reliability of human induced pluripotent stem-cell derived cardiomyocyte based safety assays using microelectrode arrays: Results from a blinded CiPA Pilot Study
Author: Millard D, Dang Q, Shi H, Zhang X, Strock C, Kraushaar U, Zeng H, Levesque P, Lu HR, Guillon JM, Wu JC, Li Y, Luerman G, Anson B, Guo L, Clements M, Abassi YA, Ross J, Pierson J, Gintant G.
Product: Maestro Pro, Maestro Edge, 心筋モジュール,
2018_jove_sanchez_assessmentoftheeffects.png
Publication
Assessment of the effects of endocrine disrupting compounds on the development of vertebrate neural network function using multi-electrode arrays
Author: Sanchez KR, Mersha MD, Dhillon HS, Temburni MK.
Product: 神経モジュール,
2018_cerebralcortex_valente_constitutiveinactivationofthe.png
Publication
Constitutive inactivation of the PRRT2 gene alters short-term synaptic plasticity and promotes network hyperexcitability in hippocampal neurons
Author: Valente P, Romei A, Fadda M, Sterlini B, Lonardoni D, Forte N, Fruscione F, Castroflorio E, Michetti C, Giansante G, Valtorta F, Tsai JW, Zara F, Nieus T, Corradi A, Fassio A, Baldelli P, Benfenati F.
Product: 神経モジュール, Maestro Pro, Maestro Edge,
Axion Bio App Note Zebrafish
Application Note
Zebrafish Assays
Author: Axion BioSystems
Product: Maestro Pro, 神経モジュール, Lumos, CytoView MEA プレート, Maestro Edge,
2018_cellstemcell_rajamani_superobesepatientderived.png
Publication
Super-obese patient-derived iPSC hypothalamic neurons exhibit obesogenic signatures and hormone responses
Author: Rajamani U, Gross AR, Hjelm BE, Sequeira A, Vawter MP, Tang J, Gangalapudi V, Wang Y, Andres AM, Gottlieb RA, Sareen D.
Product: 神経モジュール, Maestro Pro, Maestro Edge,
2018_toxicolapplpharmacol_kreir_doinvitroassays.png
Publication
Do in vitro assays in rat primary neurons predict drug-induced seizure liability in humans?
Author: Kreir M, Van Deuren B, Versweyveld S, De Bondt A, Van den Wyngaert I, Van der Linde H, Lu HR, Teuns G, Gallacher DJ.
Product: 神経モジュール, Maestro Pro, Maestro Edge,
2018_neurotoxicology_zwartsen_neurotoxicityscreeningofnew.png
Publication
Neurotoxicity screening of new psychoactive substances (NPS): effects on neuronal activity in rat cortical cultures using microelectrode arrays (MEA)
Author: Zwartsen A, Hondebrink L, Westerink RHS.
Product: 神経モジュール, Maestro Pro, Maestro Edge,
2018_brain_fruscione_prrt2controlsneuronalexcitability.png
Publication
PRRT2 controls neuronal excitability by negatively modulating Na+ channel 1.2/1.6 activity
Author: Fruscione F, Valente P, Sterlini B, Romei A, Baldassari S, Fadda M, Prestigio C, Giansante G, Sartorelli J, Rossi P, Rubio A, Gambardella A, Nieus T, Broccoli V, Fassio A, Baldelli P, Corradi A, Zara F, Benfenati F.
Product: 神経モジュール, Maestro Pro, Maestro Edge, CytoView MEA プレート,
2018 SOT Optogenetic pacing poster
Poster
Optogenetic pacing for assessment of proarrhythmic potential of drugs in induced pluripotent stem cell derived cardiomyocytes
Author: Patel D, Stohlman J, Strauss D, Blinova K.
Product: Maestro Pro, Maestro Edge, Lumos MEA プレート, Lumos, 心筋モジュール,
2018 SOT Fermini poster
Poster
Inter-individual differences in electrophysiology, pharmacology and drug responses in a cohort of hiPSC-derived cardiomyocytes: Endorsing clinical trials-in-a-dish
Author: Fermini B, Sullivan D, Chal J, Fine E, Hernandez AU, King A, Johnson J, Coyne S, Coyne KP.
Product: Maestro Pro, 心筋モジュール, Maestro Edge,
2018_cellstemcell_ziller_dissectingthefunctionalconsequences.png
Publication
Dissecting the functional consequences of de novo DNA methylation dynamics in human motor neuron differentiation and physiology
Author: Ziller MJ, Ortega JA, Quinlan KA, Santos DP, Gu H, Martin EJ, Galonska C, Pop R, Maidl S, Di Pardo A, Huang M, Meltzer HY, Gnirke A, Heckman CJ, Meissner A, Kiskinis E.
Product: 神経モジュール, Maestro Pro, Maestro Edge,