Self-Organizing 3D Human Trunk Neuromuscular Organoids

Martins JMF, Fischer C, Urzi A, Vidal R, Kunz S, Ruffault PL, Kabuss L, Hube I, Gazzerro E, Birchmeier C, Spuler S, Sauer S, Gouti M.

Cell Stem Cell, 2020

Summary:

Learn how Axion's Maestro MEA was used to record central pattern generator-like neuronal circuits from human neuromuscular organoids (NMOs).   

Keywords: central pattern generator, myasthenia gravis, neuromuscular networks, human pluripotent stem cells, spinal cord, skeletal muscle, neuromuscular junction